75762-58-2 Usage
General Description
3-Bromo-3'-fluorobenzophenone is a chemical compound with the formula C13H8BrFO. It is a white crystal solid with a molecular weight of 271.1 g/mol. 3-BROMO-3'-FLUOROBENZOPHENONE is often used as a building block in organic synthesis and pharmaceutical research. It is known for its versatile reactivity and is commonly used in the manufacture of pharmaceuticals, agrochemicals, and dyes. Additionally, 3-Bromo-3'-fluorobenzophenone has potential applications in the development of new materials and polymers due to its unique chemical structure. It is important to handle this chemical with caution as it is considered harmful if inhaled and may cause skin and eye irritation upon contact.
Check Digit Verification of cas no
The CAS Registry Mumber 75762-58-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,5,7,6 and 2 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 75762-58:
(7*7)+(6*5)+(5*7)+(4*6)+(3*2)+(2*5)+(1*8)=162
162 % 10 = 2
So 75762-58-2 is a valid CAS Registry Number.
InChI:InChI=1/C13H8BrFO/c14-11-5-1-3-9(7-11)13(16)10-4-2-6-12(15)8-10/h1-8H
75762-58-2Relevant articles and documents
Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors
Kishore Kumar,Chavarria, Gustavo E.,Charlton-Sevcik, Amanda K.,Arispe, Wara M.,MacDonough, Matthew T.,Strecker, Tracy E.,Chen, Shen-En,Siim, Bronwyn G.,Chaplin, David J.,Trawick, Mary Lynn,Pinney, Kevin G.
supporting information; experimental part, p. 1415 - 1419 (2010/07/06)
A small library of 36 functionalized benzophenone thiosemicarbazone analogs has been prepared by chemical synthesis and evaluated for their ability to inhibit the cysteine proteases cathepsin L and cathepsin B. Inhibitors of cathepsins L and B have the potential to limit or arrest cancer metastasis. The six most active inhibitors of cathepsin L (IC50 50 > 10,000 nM). The most active analog in the series, 3-bromophenyl-2′-fluorophenyl thiosemicarbazone 1, also efficiently inhibits cell invasion of the DU-145 human prostate cancer cell line.
