75782-81-9

Upstream product

• 100063-22-7 methyl 3-amino-5-phenylthiophene-2-carboxylate 
• 109-01-3 1-methyl-piperazine 
• 99972-47-1 3-amino-5-phenyl-2-thiophenecarboxylic acid 
• 98-86-2 acetophenone 
• 78583-84-3 3-chloro-3-phenylprop-2-enenitrile 

Downstream Products

• 700844-11-7 ethyl-2-cyano-3-[ (5-phenyl-3-thienyl) amino]-2-propenoate 
• 1253594-45-4 2-chloro-N-(5-phenyl-3-thienyl)acetamide 
• 135137-14-3 3-isothiocyanato-5-phenylthiophene 
• 1258958-27-8 3-(4-methoxyphenyl)-2-[(5-phenyl-3-thienyl)imino]-1,3-thiazolidin-4-one 
• 1253594-51-2 2-(5-phenyl-3-thienylimino)-1,3-thiazolidin-4-one 
• 1428907-37-2 N-(4-methoxyphenyl)-5-phenylthieno[3,2-d][1,3]thiazol-2-amine 
• 1258958-20-1 N-(4-methoxyphenyl)-N'-(5-phenyl-3-thienyl)thiourea 
• 1000409-51-7 methyl 2-(5-phenylthiophen-3-ylamino)propanoate 
• 1000409-37-9 methyl 2-(5-phenylthiophen-3-ylamino)acetate 

Relevant academic research and scientific papers

One-pot synthesis of 2-substituted thieno[3,2-b]indoles from 3-aminothiophene-2-carboxylates through in situ generated 3-aminothiophenes

A convenient protocol for one-pot synthesis of thieno[3,2-b]indoles, bearing aromatic, thien-2-yl or styryl fragments at C-2 position, from easily accessible 5-substituted 3-aminothiophene-2-carboxylates using the Fischer indolization reaction, was develo

Thienopyridone derivative, method for preparing the same and pharmaceutical composition comprising the same

The present invention relates to a thienopyridone derivative, a production method thereof, and a pharmaceutical composition comprising the same and, more particularly, to a novel thienopyridone derivative comprising various substituents, a production method thereof, and a pharmaceutical composition for preventing or treating cancer, comprising the same as active ingredient.COPYRIGHT KIPO 2017

Synthesis of novel thieno[3,2-b]quinolines and thieno[3,2-d][1,3]thiazoles

New heterocyclic 2-Aryl-9-chloro-5,6,7,8-tetrahydrothieno[3,2-b]quinoline derivatives [Aryl-CTTQ] (2a-e) and 5-arylthieno[3,2-d][1,3]thiazol-2-amine derivatives[Aryl-TZA] (6a-e)were achieved in good yields starting from 5-aryl-3-aminothiophene-2-carboxyli

Synthesis of novel 2-thienylimino-1,3-thiazolidin-4-ones

The preparation of new 2-thienylimino-1,3-thiazolidin-4-ones from 3-aminothiophene-2-carboxylate using an easy four-step procedure is described. Georg Thieme Verlag Stuttgart New York.

PTP1B inhibitors

This invention relates to modulating (e.g., inhibiting) protein tyrosine phosphatase 1b (PTP1b).

Thieno[3,2-b]pyridine-6-carbonitriles and thieno[2,3-b]pyridine-5-carbonitriles as protein kinase inhibitors

This invention provides compounds of Formula (1a)-(1f), II wherein: X, m, n, q, R1, R2, R3, R4, R5, R6, R7, R8, R9, Y, Q, Z, Z′, Z′″, Z″ and J are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, myocardial infarction, neuropathic pain, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.

THIENO[3,2-b]PYRIDINE-6-CARBONITRILES AND THIENO[2,3-b]PYRIDINE-5-CARBONITRILES AS PROTEIN KINASE INHIBITORS

This invention provides compounds of Formula (1 a) - (1f) wherein:X, R1, and R2 are defined hereinbefore in the specification, which are useful in the treatment of cancer, stroke, osteoporosis, polycystic kidney disease, autoimmune disease, rheumatoid arthritis, and transplant rejection and process for producing said compounds.