99972-47-1

Basic information

• Product Name: 2-Thiophenecarboxylicacid,3-amino-5-phenyl-
• Synonyms: 2-Thiophenecarboxylicacid,3-amino-5-phenyl-;3-amino-5-phenyl-2-Thiophenecarboxylic acid;CADPUALMFMAHDY-UHFFFAOYSA-N
• CAS NO: 99972-47-1
• Molecular Formula: C₁₁H₉NO₂S
• Molecular Weight: 219.25966
• Mol File: 99972-47-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Thiophenecarboxylicacid,3-amino-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiophenecarboxylicacid,3-amino-5-phenyl-(99972-47-1)
• EPA Substance Registry System: 2-Thiophenecarboxylicacid,3-amino-5-phenyl-(99972-47-1)

Safety Data

• Hazardous Substances Data: 99972-47-1(Hazardous Substances Data)

Upstream product

• 78583-84-3 3-chloro-3-phenylprop-2-enenitrile 
• 98-86-2 acetophenone 
• 100063-22-7 methyl 3-amino-5-phenylthiophene-2-carboxylate 
• 88534-50-3 ethyl 3-amino-5-(phenyl)thiophene-2-carboxylate 

Downstream Products

• 122375-70-6 3-amino-5-phenylthiophene-2-carboxamide 
• 845865-05-6 3-(3-benzyl-ureido)-5-phenyl-thiophene-2-carboxylic acid 
• 75782-81-9 5-phenyl-3-thiopheneamine 
• 478028-43-2 6-phenyl-2,4-dihydro-1H-thieno[3,2-d][1,3]oxazine-2,4-dione 
• 1585969-82-9 3-([1,1'-biphenyl]-4-ylcarboxamido)-5-phenylthiophene-2-carboxylic acid 
• 477326-27-5 methyl 3-([1,1'-biphenyl]-4-ylcarboxamido)-5-phenylthiophene-2-carboxylate 
• 100063-22-7 methyl 3-amino-5-phenylthiophene-2-carboxylate 
• 1428907-29-2 9-chloro-2-phenyl-5,6,7,8-tetrahydrothieno[3,2-b]quinoline 
• 1428907-37-2 N-(4-methoxyphenyl)-5-phenylthieno[3,2-d][1,3]thiazol-2-amine 
• 1258958-20-1 N-(4-methoxyphenyl)-N'-(5-phenyl-3-thienyl)thiourea 

Relevant articles and documents

Exploring the chemical space of ureidothiophene-2-carboxylic acids as inhibitors of the quorum sensing enzyme PqsD from Pseudomonas aeruginosa

Pseudomonas aeruginosa employs a quorum sensing (QS) communication system that makes use of small diffusible molecules. Among other effects, the QS system coordinates the formation of biofilm which decisively contributes to difficulties in the therapy of

Synthesis of novel 2-thienylimino-1,3-thiazolidin-4-ones

The preparation of new 2-thienylimino-1,3-thiazolidin-4-ones from 3-aminothiophene-2-carboxylate using an easy four-step procedure is described. Georg Thieme Verlag Stuttgart New York.

Hit-to-lead studies: The discovery of potent, orally active, thiophenecarboxamide IKK-2 inhibitors

A hit-to-lead optimisation programme was carried out on the thiophenecarboxamide high throughput screening hits 1 and 2 resulting in the discovery of the potent and orally bioavailable IKK-2 inhibitor 22.