757893-62-2Relevant academic research and scientific papers
Rhodium-Catalyzed meta-Selective C?H Carboxylation Reaction of 1,1-Diarylethylenes via Hydrorhodation-Rhodium Migration
Caner, Joaquim,Iwasawa, Nobuharu,Saito, Takanobu,Toriumi, Naoyuki
, p. 23349 - 23356 (2021/09/18)
A meta-selective C?H carboxylation reaction of 1,1-diarylethylene derivatives with CO2 by using a rhodium catalyst with NaOiPr as a stoichiometric reductant has been achieved. Together with hydrogenation of the ethylene moiety, a carboxyl group was introduced to the meta-position of the aryl ring with high selectivity over the ortho-positions. Experimental and computational mechanistic studies indicate that this carboxylation reaction proceeds via hydrorhodation on the ethylene moiety, followed by 1,4-rhodium migration and successive 1,2-rhodium migration on the aryl ring. The use of a bulky phosphine ligand seems to be the key to this unusual aryl-to-aryl 1,2-rhodium shift.
Mesoionic Carbene-Iridium Complex Catalyzed Ortho-Selective Hydrogen Isotope Exchange of Anilines with High Functional Group Tolerance
Cao, Lei,Huang, Linwei,Huang, Shiqing,Liu, Wei,Yan, Xiaoyu,Zhang, Gang,Zhang, Zengyu,Zhao, Peng
supporting information, (2020/03/13)
Mesoionic carbene-iridium complex 1a has been investigated in the hydrogen isotope exchange (HIE) reaction of anilines. By employing 1 mol % of 1a as catalyst, anilines were selectively deuterated at the ortho-position with high deuteration levels. High ortho-selectivity was observed for anilines with various competing directing groups, which is in contrast with catalytic results of Kerr's catalysts.
Parallel NMR based on solution magnetic-susceptibility differences. Application to isotopic effects on self-diffusion
Fries, Pascal H.,Imbert, Daniel
experimental part, p. 2048 - 2054 (2011/07/30)
Different susceptibility NMR line shifts can be induced in distinct liquid solutions by dissolving different concentrations of complexes of paramagnetic lanthanide Ln3+ ions. We show how these solutions, put in capillaries, can be simultaneousl
Microwave mediated hydrogen deuterium exchange: A rapid synthesis of 2H-substituted benzimidazole
Vaidyanathan, Srirajan,Surber, Bruce W.
, p. 5195 - 5197 (2007/10/03)
Deuterium aromatic substituted compounds were prepared by microwave irradiation of the parent unlabeled compounds in the presence of deuterium oxide and deuterium chloride. The percentage of deuterium incorporation was investigated under various reaction
A Study of Gaseous Benzenium and Toluenium Ions generated from 1,4-Dihydro- and 1-Methyl-1,4-dihydro-benzoic Acids
Kuck, Dietmar,Schneider, Jens,Gruetzmacher, Hans-Friedrich
, p. 689 - 696 (2007/10/02)
Gaseous benzenium C6H7(1+) (1) and toluenium C7H9(1+) (2) ions have been generated by mass spectrometric loss of .CO2H from the corresponding 1,4-dihydrobenzoic acids (3) and (4), and their fragmentations after ca. 10 μs have been investigated by means of mass-analysed ion kinetic energy (MIKE) spectrometry of some 2H and 13C labelled analogues.Metastable C6H7(1+) ions eliminate H2 after proton randomization, whereas metastable C7H9(1+) ions expel both H2 and CH4 after incomplete proton equilibration.In particular, 40percent of C7H9(1+) ions randomize all their carbon and hydrogen atoms prior to loss of CH4, and 60percent of C7H9(1+) ions lose the original methyl group along with a hydrogen atom from the (proton-equilibrated) benzenium ring, accompanied by a slow and incomplete exchange between the hydrogen atoms of the ring and the methyl group.It is suggested that loss of both CH4 and H2 occur via the (ipso-)toluenium ion (2).The role of a non-classical C7H9(1+) isomer, phenylmethonium ion (6), is discussed since striking similarities are found compared * adducts from ion-molecule reactions described in the literature.
