37960-84-2

Usage

Uses

Benzoic-3,5-d2 Acid (CAS# 37960-84-2) is a useful isotopically labeled research compound.

Upstream product

• 16954-38-4 toluene-3,5-d₂ 
• 1611-92-3 3,5-dibromotoluene 
• 51-36-5 3,5-dichlorobenzoic acid 
• 22589-50-0 4-amino-3,5-dibromo-acetophenone 
• 106-40-1 4-bromo-aniline 
• 757893-62-2 3,5-dideuterio-4-bromoaniline 
• 618-58-6 3,5-dibromobenzoic acid 
• 14401-73-1 3,5-dibromoacetophenone 
• 124-38-9 carbon dioxide 
• 7291-07-8 1-bromo-3,5-dideuteriobenzene 

Downstream Products

• 98752-36-4 3,5-dideuterio-1,4-dihydrobenzoic acid 

Relevant academic research and scientific papers

Aqueous Oxidations Started by TiO2 Photoinduced Holes Can Be a Rate-Determining Step

In aqueous TiO2 photocatalytic hydroxylation of weakly polar aromatics, a series of inverse H/D KIEs of 0.7–0.8 were observed, which is different than the normal H/D kinetic isotope effects (KIEs) usually observed for polar aromatics. This result indicated that the oxidation started by photo-induced hvb + can be the rate-determining step.

A convenient method for palladium-catalyzed reductive deuteration of organic substrates using deuterated hypophosphite in D2O

A convenient method for the deuteration of organic substrates using deuterated hypophosphite as the deuterium source was investigated. Transfer deuteration of organic substrates, such as aromatic halides, alkenes, alkynes, epoxides, and O-benzyl derivativ

PREPARATION OF DEUTERIATED 1-PHENYLETHANOLS BY REDUCTIVE DEHALOGENATION OF THE CORRESPONDING HALOGENOACETOPHENONES WITH RANEY ALLOYS IN AN ALKALINE DEUTERIUM OXIDE SOLUTION

Deuteriated 1-phenylethanols were prepared by reductive dehalogenation of the corresponding halogenoacetophenones with Raney Ni-Al and Cu-Al alloys in 5percent NaOD-D2O solution.It was found that the Ni-Al alloy introduced greater than expected numbers of deuterium atoms in the phenyl ring, but the expected deuteriated 1-phenylethanols were obtained in high yield and in high isotopic purity when Raney Cu-Al alloy was used.

A Study of Gaseous Benzenium and Toluenium Ions generated from 1,4-Dihydro- and 1-Methyl-1,4-dihydro-benzoic Acids

Gaseous benzenium C6H7(1+) (1) and toluenium C7H9(1+) (2) ions have been generated by mass spectrometric loss of .CO2H from the corresponding 1,4-dihydrobenzoic acids (3) and (4), and their fragmentations after ca. 10 μs have been investigated by means of mass-analysed ion kinetic energy (MIKE) spectrometry of some 2H and 13C labelled analogues.Metastable C6H7(1+) ions eliminate H2 after proton randomization, whereas metastable C7H9(1+) ions expel both H2 and CH4 after incomplete proton equilibration.In particular, 40percent of C7H9(1+) ions randomize all their carbon and hydrogen atoms prior to loss of CH4, and 60percent of C7H9(1+) ions lose the original methyl group along with a hydrogen atom from the (proton-equilibrated) benzenium ring, accompanied by a slow and incomplete exchange between the hydrogen atoms of the ring and the methyl group.It is suggested that loss of both CH4 and H2 occur via the (ipso-)toluenium ion (2).The role of a non-classical C7H9(1+) isomer, phenylmethonium ion (6), is discussed since striking similarities are found compared * adducts from ion-molecule reactions described in the literature.

Preparation of All the Possible Ring-deuteriated Benzoic Acids by Reductive Dehalogenation of the Corresponding Halogenobenzoic Acids with Raney Alloys in an Alkaline Deuterium Oxide Solution

All the possible undeuteriated benzoic acids were prepared mainly by treatment of the corresponding bromobenzoic acid with Raney Cu-Al alloy in 10percent NaOD-D2O solution. 5>Benzoic acid was obtained from pentafluorobenzoic acid by a similar reaction.However, only 4>benzoic acid was prepared by decarboxylation of 4>phthalic acid.