757956-01-7

Upstream product

• 77118-87-7 (S)-1-Phenyl-3-buten-1-ol 
• 100-52-7 benzaldehyde 
• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 942154-15-6 C₁₅H₂₀O₃ 
• 942154-16-7 4-(iodomethyl)-6-phenyl-1,3-dioxan-2-one 

Downstream Products

• 942154-17-8 (1S,3R)-3,4-epoxy-1-tert-butyldimethylsilyloxy-1-phenyl-butane 
• 929289-07-6 (4S,6S)-6-(tert-butyldimethylsilyl)oxy-4-hydroxy-6-phenyl-1-hexene 
• 929289-08-7 (1S,3S,2E)-1-(tert-butyldimethylsilyloxy)-5-hydroxy-1,7-diphenylhept-2-en-3-one 
• 326477-55-8 (4S,6S)-(-)-4-Hydroxy-6-phenylpiperidin-2-one 
• 259856-83-2 (2S,4R)-(-)-2-Phenylpiperidine-4-ol 
• 259856-87-6 (2S,4R)-(-)-4-Acetoxy-2-phenyl-1-trifluoroacetylpiperidine 

Relevant academic research and scientific papers

AN ENANTIOSELECTIVE PROCESS FOR THE SYNTHESIS OF (2S,4R)-4-HYDROXYPIPECOLIC ACID

The present invention relates to an improved process for synthesis of 4-hydroxy pipecolic acid. The present invention relates to an improved enantioselective process for the synthesis of (2S,4R)-4-hydroxypipecolic acid via Co(III) (salen)-catalyzed two stereocentered Hydrolytic Kinetic Resolution (HKR) of racemic 1,3-azido epoxide with good yields and high optical purity without any protecting groups. 10 31

Synthesis of diospongin A

A stereoselective synthesis of Diospongin A using a cross-metathesis-intramolecular Michael addition has been achieved.

A facile synthetic route to (+)-allosedamine via hydrolytic kinetic resolution and olefin metathesis

A concise synthesis of (+)-allosedamine has been achieved using cobalt-catalyzed hydrolytic kinetic resolution (HKR) and ruthenium-catalyzed ring closing metathesis (RCM) as two key steps, in which HKR was used to introduce both stereogenic centers in the natural compound with a high degree of diastereomeric ratio and cyclization was carried out with the well developed RCM procedure.