757977-16-5

Upstream product

• 757977-14-3 (3R,4S)-1-benzoyl-3-O-triisopropylsilyloxy-4-(o-allylphenyl)azetidin-2-one 
• 172482-21-2 4-deacetyl-4-acryloyl-7-O-triethylsilylbaccatin III 
• 673855-68-0 (+)-(3R,4S)-3-acetoxy-4-(2-bromophenyl)-1-(4-methoxyphenyl)azetidin-2-one 
• 6630-33-7 ortho-bromobenzaldehyde 
• 38018-60-9 (E)-N-(2-bromobenzylidene)-4-methoxyaniline 
• 13154-24-0 triisopropylsilyl chloride 
• 860782-19-0 1-dimethylsilyl-4-deacetyl-4-acryloyl-7-O,10-O,13-O-tris-triethylsilylbaccatin III 
• 860782-21-4 4-deacetyl-4-acryloylbaccatin III 
• 860782-20-3 4-deacetyl-4-acryloyl-10-deacetylbaccatin III 
• 860782-59-8 4-(2-allyl-phenyl)-1-(4-methoxy-phenyl)-3-triisopropylsilanyloxy-azetidin-2-one 
• 860782-81-6 4-(2-bromo-phenyl)-1-(4-methoxy-phenyl)-3-triisopropylsilanyloxy-azetidin-2-one 
• 757977-12-1 4-(2-allyl-phenyl)-3-triisopropylsilanyloxy-azetidin-2-one 
• 941672-61-3 4-(2-bromo-phenyl)-3-hydroxy-1-(4-methoxy-phenyl)-azetidin-2-one 

Downstream Products

• 860782-80-5 C₄₉H₅₁NO₁₄ 
• 757977-17-6 C₄₉H₅₁NO₁₄ 
• 860782-23-6 C₆₄H₈₅NO₁₄Si₂ 
• 860782-79-2 C₆₄H₈₅NO₁₄Si₂ 

Relevant academic research and scientific papers

Evaluation of the tubulin-bound paclitaxel conformation: Synthesis, biology, and SAR studies of C-4 to C-3′ bridged paclitaxel analogues

The important anticancer drug paclitaxel binds to the β-subunit of the ββ-tubulin dimer in the microtubule in a stoichiometric ratio, promoting microtubule polymerization and stability. The conformation of microtubule-bound drug has been the subject of in