75806-97-2

Basic information

• Product Name: N^G-Mds-Arg
• Synonyms: N^G-Mds-Arg
• CAS NO: 75806-97-2
• Molecular Weight: 372.445
• Mol File: 75806-97-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N^G-Mds-Arg(CAS DataBase Reference)
• NIST Chemistry Reference: N^G-Mds-Arg(75806-97-2)
• EPA Substance Registry System: N^G-Mds-Arg(75806-97-2)

Safety Data

• Hazardous Substances Data: 75806-97-2(Hazardous Substances Data)

Upstream product

• 79590-30-0 Z-Arg(Mds)-OH*CHA 
• 75813-41-1 N^α-benzyloxycarbonyl-N^G-(4-methoxy-2,6-dimethylbenzenesulphonyl)arginine 
• 1234-35-1 Z-Arg-OH 
• 55661-08-0 4-methoxy-2,6-dimethylbenzenesulfonyl chloride 

Downstream Products

• 80760-69-6 Boc-Arg(Mds)-Pro-Lys(Boc)-Pro-OH 
• 74-79-3 L-arginine 

Relevant articles and documents

Further Studies on the Use of Multi-substituted Benzenesulfonyl Groups for Protection of the Guanidino Function of Arginine

Various multi-substituted benzenesulfonyl protecting groups for the guanidino function of arginine, removable under mild conditions such as with trifluoroacetic acid (TFA)-thioanisole, were studied.Among them, the 4-methoxy-2,6-dimethylbenzenesulfonyl (Mds) group, the 2,3,4,5,6-pentamethylbenzenesulfonyl (Pme) group, and the 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr) group were found to be useful.Both Mds and Pme show considerable resistance to TFA and, therefore, are suitable for procedures in which the intermediates are deprotected by TFA treatment, while Mtr is the most useful protecting group when TFA treatment is not necessary.Keywords---4-methoxy-2,6-dimethylbenzenesulfonyl (Mds); 2,4,6-trimethoxybenzenesulfonyl (Mtb); 2,3,4,5,6-pentamethylbenzenesulfonyl (Pme); 4-methoxy-2,3,6-trimethylbenzenesulfonyl (Mtr); trifluoroacetic acid-thioanisole deprotection