75814-54-9Relevant academic research and scientific papers
Fe(0)-mediated synthesis of tri- and tetra-substituted olefins from carbonyls: An environmentally friendly alternative to Cr(II)
Falck,Bejot, Romain,Barma, Deb K.,Bandyopadhyay, Anish,Joseph, Suju,Mioskowski, Charles
, p. 8178 - 8182 (2006)
Fe(0) was investigated as a cost-effective, environmentally friendly alternative to Cr(II) for the olefination of carbonyls by activated polyhalides. In many instances, Fe(0) was equivalent or superior to Cr(II). Notably, Fe(0), but not Cr(II), proved com
Wittig-type Reaction of Dimetallated Carbodianion Species as Produced by Zinc Reduction of gem-Polyhalogen Compounds in the Presence of Levis Acids
Takai, Kazuhiko,Hotta, Yuji,Oshima, Koichiro,Nozaki, Hitosi
, p. 1698 - 1702 (2007/10/02)
Treatment of R1COR2 with a suspension prepared from diiodomethane, trimethylaluminium and excess zinc in tetrahydrofuran at room temperature affords olefins R1R2C=CH2 in fair (R1,R2=alkyl) to good (R1=alkyl, R2=H) yields.The ketone methylenation is better carried with another system consisting of CH2Br2-Zn-TiCl4.Ketones and aldehydes are transformed into α-chloro α,β-unsaturated esters or α,β-unsaturated esters in good yields on treatment with methyl trichloroacetate or t-butyl dichloroacetate (ethyl dibromoacetate) in the presence of diethylaluminium chloride and zinc.
