75821-15-7

Upstream product

• 23767-38-6 2-methylsulphonyl-5-(4-chlorophenyl)-1,3,4-oxadiazole 
• 536-40-3 4-chlorobenzoic acid hydrazide 
• 1126-46-1 Methyl 4-chlorobenzoate 
• 74-11-3 para-chlorobenzoic acid 
• 23766-28-1 5-(4-chlorophenyl)-1,3,4-oxadiazole-2-thiol 
• 23767-37-5 2-(4-chloro-phenyl)-5-methylsulfanyl-[1,3,4]oxadiazole 

Downstream Products

• 473725-34-7 N-[5-(4-chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-N'-cyclohexylidene-hydrazine 
• 861229-53-0 benzoic acid N'-[5-(4-chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-hydrazide 
• 1394252-29-9 C₁₅H₁₁ClN₄O₂ 
• 1394252-30-2 C₁₆H₁₃ClN₄O₂ 
• 473725-78-9 4-[5-(4-chloro-phenyl)-[1,3,4]oxadiazol-2-ylamino]-1-thia-4-aza-spiro[4.5]decan-3-one 
• 861229-52-9 2-chloro-benzoic acid N'-[5-(4-chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-hydrazide 

Relevant academic research and scientific papers

Synthesis and spectral characterization of Zn(II) microsphere series for antimicrobial application

Microsphere series have been synthesized by reacting zinc(II) acetate dihydrate with Schiff bases derived from 2-hydrazino-5-[substituted phenyl]-1,3,4-thiadiazole/oxadiazole/triazole with salicylaldehyde. Elemental analysis suggests that the complexes have 1:2 and 1:1 stoichiometry of the type [Zn(L)2(H2O)2] and [Zn(L′)(H 2O)2]; LH = Schiff bases derived from 2-hydrazino-5- [substituted phenyl]-1,3,4-thia/oxadiazole with salicylaldehyde; L′H 2 = Schiff bases derived from 3-(substituted phenyl)-4-amino-5- hydrazino-1,2,4-triazole and salicylaldehyde and were characterized by elemental analyses, IR, 1H NMR and 13C NMR spectral data. Scanning electron microscopy (SEM) showed that synthesized materials have microsphere like structure and there EDX analysis comparably matches with elemental analysis. For the antimicrobial application Schiff bases and their zinc(II) complexes were screened for four bacteria e.g. Bacillus subtilis, Pseudomonas aeruginosa, Salmonella typhi, Streptococcus pyogenes and four fungi e.g. Cyrtomium falcatum, Aspergillus niger, Fusarium oxysporium and Curvularia pallescence by the reported method. Schiff base and Zn(II) compounds showed significant antimicrobial activities. However, activities increase upon chelation. Thermal analysis (TGA) data of compound (10) showed its stability up to 300 °C.

Synthesis, structures, and fungitoxicity of novel organophosphorus compounds

A series of biologically active organophosphorus compounds have been synthesized by the reactions of O,O-diethylchlorophosphate with Schiff bases derived from 5-(phenyl/substituted phenyl)-2-hydrazino-1,3,4-oxadiazole and salicylaldehyde/2-hydroxyacetophenone. The compounds have been characterized on the basis of analyses and spectral (IR, 1H, 13C NMR) data. Fungicidal activities of these derivatives against Colletotrichum falcatum, Fusarium oxysporum, and Curvularia pallescence have been evaluated. All compounds showed moderate to significant antifungal activity.

A new route to synthesis of 3,6-diaryl-1,2,4-triazolo[3,4-b]1,3,4- oxadiazoles

Five new 3,6-diaryl-1,2,4-triazolo[3,4-b]1,3,4-oxadiazole derivatives were synthesized by 9 steps from aromatic acids and evaluated for their activities of anticancer and antibacteria. The structures of all new compounds synthesized were elucidated by MS,