75821-60-2

Upstream product

• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 56246-53-8 (+)-ethyl cincholoiponate 
• 474964-21-1 cinchonine 
• 26599-66-6 (+/-)-trans-3-ethyl-4-piperidineacetic acid ethyl ester 
• 56774-65-3 ((3S,4S)-6-Ethoxy-3-ethyl-2,3,4,5-tetrahydro-pyridin-4-yl)-acetic acid ethyl ester 

Downstream Products

• 56193-96-5 (3S,4S)-(-)-1-(3,4-dimethoxyphenethyl)-3-ethyl-4-piperidineethanol 
• 56193-98-7 (3R,4R)-(+)-1-(3,4-dimethoxyphenethyl)-3-ethyl-4-piperidineethanol 
• 56151-97-4 (3R,4S)-(-)-1-(3,4-dimethoxyphenethyl)-3-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 56151-99-6 (4S,5R)-(-)-1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid 
• 56193-97-6 (4R,5R)-(+)-1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid 
• 56151-96-3 (4S,5R)-(-)-1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 56152-02-4 (4R,5R)-(+)-1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 75821-65-7 (3S,4S)-(+)-1-(3,4-dimethoxyphenethyl)-3-ethyl-2-oxo-4-piperidineacetic acid 
• 71333-94-3 (4S,5R)-1-<2-(3,4-dimethoxyphenyl)-2-hydroxyethyl>-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 75821-62-4 (4S)-1-<2-(3,4-dimethoxyphenyl)-2-hydroxyethyl>-3-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 63987-78-0 {(3R,4S)-1-[2-(3,4-Dimethoxy-phenyl)-2-hydroxy-ethyl]-3-ethyl-piperidin-4-yl}-acetic acid ethyl ester; compound with carbonic acid 
• 56151-98-5 (3S,4S)-(+)-1-(3,4-dimethoxyphenethyl)-3-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 75821-62-4 (+/-)-1-<2-(3,4-dimethoxyphenyl)-2-hydroxyethyl>-3-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 71333-94-3 (+/-)-trans-1-<2-(3,4-dimethoxyphenyl)-2-hydroxyethyl>-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 

Relevant academic research and scientific papers

Quinolizidines-V. A novel synthetic route to Ipecac alkaloids through chemical incorporation of ethyl cincholoiponate derived from the cinchona alkaloid cinchonine

A new synthetic route to (-)-emetine (1) and related Ipecac alkaloids has been exploited in terms of the synthesis of the tricyclic ester (-)-30 from ethyl cincholoiponate [(+)-4], a degradation product of the Cinchona alkaloid cinchonine (7). The steps i