56152-02-4

Upstream product

• 56151-99-6 (4S,5R)-(-)-1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid 
• 75821-60-2 (3R,4S)-(+)-1-(3,4-dimethoxyphenacyl)-3-ethyl-4-piperidineacetic acid ethyl ester 
• 64-17-5 ethanol 
• 56151-99-6 (5R)-1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid 
• 71333-94-3 (+/-)-trans-1-<2-(3,4-dimethoxyphenyl)-2-hydroxyethyl>-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 75821-62-4 (+/-)-1-<2-(3,4-dimethoxyphenyl)-2-hydroxyethyl>-3-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 78867-73-9 1-(3,4-dimethoxyphenethyl)-5-ethyl-5,6-dihydro-2(1H)-pyridinone 
• 105-53-3 diethyl malonate 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 26599-66-6 (+/-)-trans-3-ethyl-4-piperidineacetic acid ethyl ester 
• 56151-96-3 (4S,5R)-(-)-1-(3,4-dimethoxyphenethyl)-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 
• 474964-21-1 cinchonine 
• 96790-30-6 (3R,4R)-(+)-6-ethoxy-3-ethyl-2,3,4,5-tetrahydro-4-pyridineacetic acid ethyl ester 
• 115075-62-2 (4R,5R)-1-(3,4-dimethoxyphenacyl)-5-ethyl-2-oxo-4-piperidineacetic acid ethyl ester 

Downstream Products

• 56193-98-7 (3R,4R)-(+)-1-(3,4-dimethoxyphenethyl)-3-ethyl-4-piperidineethanol 

Relevant academic research and scientific papers

QUINOLIZIDINES. XXIII. AN ALTERNATIVE SYNTHETIC ROUTE TO BENZOQUINOLIZIDINE-TYPE ALANGIUM ALKALOIDS FROM ETHYL CINCHOLOIPONATE

The trans lactam acid (+)-XX was isolated in good yield in the form of the 4-methoxybenzyl ester (+)-XXV from an equilibrated 66:34 mixture of the trans and cis isomers , which was obtained by thermal cis-trans isomerization of the cis

AN ALTERNATIVE ROUTE TO (+/-)-EMETINE AND (+/-)-DIHYDROCORYNANTHEINE

An alternatie synthesis of (+/-)-emetine(11) and (+/-)-dihydrocorynantheine(13) has been developed in formal sense starting from methyl 3-formylhexanoate(3).

Quinolizidines-V. A novel synthetic route to Ipecac alkaloids through chemical incorporation of ethyl cincholoiponate derived from the cinchona alkaloid cinchonine

A new synthetic route to (-)-emetine (1) and related Ipecac alkaloids has been exploited in terms of the synthesis of the tricyclic ester (-)-30 from ethyl cincholoiponate [(+)-4], a degradation product of the Cinchona alkaloid cinchonine (7). The steps i