758716-24-4Relevant academic research and scientific papers
An intramolecular Diels-Alder approach to the eunicellins: Enantioselective total syntheses of ophirin B and astrogorgin
Crimmins, Michael T.,Brown, Brandon H.,Plake, Hilary R.
, p. 1371 - 1378 (2007/10/03)
The enantioselective syntheses of the eunicellins ophirin B and astrogorgin have been completed. Ring-closing metatheses provide efficient access to the oxonene rings, and highly diastereoselective intramolecular Diels-Alder reactions resulted in the form
Discovery of a practical direct O2-coupled wacker oxidation with Pd[(-)-sparteine]Cl2
Cornell, Candace N.,Sigman, Matthew S.
, p. 4117 - 4120 (2007/10/03)
The discovery of a direct O2-coupled Wacker oxidation with use of balloon pressure of O2 and low catalyst loading is described. Use of (-)-sparteine as a ligand on Pd prevents olefin isomerization and leads to selective formation of methyl ketones from terminal olefins in good yields. Oxidation of enantiomerically enriched substrates is reported with no observed racemization.
Ah intramolecular Diels-Alder approach to the eunicelins: Enantioselective total synthesis of ophirin B
Crimmins, Michael T.,Brown, Brandon H.
, p. 10264 - 10266 (2007/10/03)
The enantioselective synthesis of the eunicellin ophirin B has been completed. A ring-closing metathesis provides efficient access to the oxonene ring, and a highly diastereoselective intramolecular Diels-Alder reaction results in the formation of the hyd
