75884-70-7

Basic information

• Product Name: 6-BROMOPHTHALAZIN-1(2H)-ONE
• Synonyms: 6-BROMOPHTHALAZIN-1(2H)-ONE;6-Bromophthalazinone;6-Bromo-2,3-Bisphthalazinone;6-broMo-1,2-dihydrophthalazin-1-one;1(2H)-Phthalazinone, 6-broMo-;6-bromo-2H-phthalazin-1-one;6-Bromophthalazin-1(4H)-one
• CAS NO: 75884-70-7
• Molecular Formula: C₈H₅BrN₂O
• Molecular Weight: 225.0421
• Product Categories: Aldehyde
• Mol File: 75884-70-7.mol
• Article Data: 17

Chemical Properties

• Melting Point: 280-283 °C
• Boiling Point: 347.6 °C at 760 mmHg
• Flash Point: 164 °C
• Appearance: /Solid
• Density: 1.82 g/cm³
• Vapor Pressure: 1.26E-09mmHg at 25°C
• Refractive Index: 1.721
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 11.66±0.20(Predicted)
• CAS DataBase Reference: 6-BROMOPHTHALAZIN-1(2H)-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMOPHTHALAZIN-1(2H)-ONE(75884-70-7)
• EPA Substance Registry System: 6-BROMOPHTHALAZIN-1(2H)-ONE(75884-70-7)

Safety Data

• Hazardous Substances Data: 75884-70-7(Hazardous Substances Data)

Usage

General Description

6-Bromophthalazin-1(2H)-one is a chemical compound with the molecular formula C8H5BrN2O. It is a heterocyclic compound that contains a bromine atom and a ketone functional group. 6-Bromophthalazin-1(2H)-one is used in the synthesis and development of pharmaceuticals, agrochemicals, and other organic compounds. It has also been found to exhibit antiviral and antitumor properties. This chemical compound has potential applications in drug discovery and medicinal chemistry, and has been the subject of research for its biological activities and potential therapeutic uses.

InChI:InChI=1/C8H5BrN2O/c9-6-1-2-7-5(3-6)4-10-11-8(7)12/h1-4H,(H,11,12)

Upstream product

• 573675-39-5 5-bromo-3-hydroxyisoindoline-1-one 
• 64169-34-2 5-bromophthalide 
• 102126-70-5 5-bromo-3-bromo-3H-isobenzofuran-1-one 
• 99548-55-7 4-bromo-2-methyl-benzoic acid methyl ester 
• 102126-71-6 5-bromo-3-hydroxyphthalide 
• 6941-75-9 5-Bromoisoindoline-1,3-dione 

Downstream Products

• 897661-90-4 6-(4-chlorophenyl)-2H-phthalazin-1-one 
• 1234616-69-3 6-bromo-2-methylphthalazin-1(2H)-one 
• 1416977-97-3 (E)-2-(6-(3-(3,5-Dichloro-4-fluorophenyl)-4,4,4-trifluorobut-1-en-1-yl)-1-oxophthalazin-2(1H)-yl)-N-(2,2,2-trifluoroethyl)acetamide 
• 1416980-17-0 (E)-2-(6-(3-(3,5-Dichloro-4-fluorophenyl)-4,4,4-trifluorobut-1-en-1-yl)-1-oxophthalazin-2(1H)-yl)acetic acid 

Relevant articles and documents

Histone histone deacetylase inhibitor and application thereof

The invention provides a histone histone deacetylase inhibitor and application thereof. Specifically, the invention provides a compound of formula (I) as shown in the specification, and a pharmaceutically acceptable salt of the compound, and in the formula, the groups are defined as shown in the specification. The invention further provides a preparation method of the compound. The compound of formula (I), which is provided by the invention, can be adopted to treat a series of diseases mediated by histone histone deacetylases by inhibiting histone histone deacetylases (HDACs), particularly type-I histone histone deacetylases (subtypes such as HDAC1 and HDAC3), particularly including tumor diseases such as solid tumor and leukemia, neurodegenerative diseases, and the like.

PROTOZOAN PARASITE GROWTH INHIBITORS

Compounds and methods for inhibiting growth of a protozoan parasite. Methods of treating a protozoan parasite infection in a subject by administering a therapeutically effective amount of a compound as disclosed herein. The compounds and methods can be us

PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO

This document discloses molecules having the following formula (“Formula One”): and processes associated therewith.