75898-43-0

Upstream product

• 640-68-6 D-Val-OH 
• 115-11-7 isobutene 

Downstream Products

• 197965-90-5 2(R)-(4-methoxybenzenesulfonylamino)-3-methylbutyric acid tert-butyl ester 
• 873923-16-1 2-(4-chloro-3-nitro-benzenesulfonylamino)-3-methyl-butyric acid tert-butyl ester 
• 910630-90-9 (R)-3-Methyl-2-[(Z)-(7S,8R,9S)-7,8,9-tris-benzyloxy-9-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-non-5-enoylamino]-butyric acid tert-butyl ester 
• 960113-36-4 tert-butyl (R)-2-(4-(dimethylamino)phenylsulfonamido)-3-methylbutanoate 
• 193810-39-8 tert-butyl (R)-2-(4-nitrophenylsulfonamido)-3-methylbutanoate 
• 161315-62-4 N-[(4-methoxyphenyl)sulfonyl]-D-valine tert-butyl ester 
• 873923-18-3 2-[(biphenyl-4-sulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-butyric acid tert-butyl ester 
• 854371-76-9 D-2-[4'-(benzofuran-2-ylmethoxy)biphenyl-4-sulfonylamino]-3-methylbutyric acid tert-butyl ester 
• 854372-24-0 benzofuran-2-carboxylic acid 4'-(1-tert-butoxycarbonyl-2-methylpropylsulfamoyl)biphenyl-4-yl ester 
• 854372-23-9 tert-butyl N-[(4'-{[(3-methyl-1-benzofuran-2-yl)carbonyl]oxy}-1,1'-biphenyl-4-yl)sulfonyl]-D-valinate 

Relevant academic research and scientific papers

STUDIES ON AMINO ACIDS AND PEPTIDES X. HPLC-MEDIATED TEST OF 2,4-BIS(4-METHOXYPHENYL)-1,3,2,4-DITHIADIPHOSPHETANE 2,4-DISULFIDE (LAWESSONS'S REAGENT) AS A RACEMIZATIONFREE COUPLING REAGENT IN PEPTIDE SYNTHESIS

The easily available 2,4-bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide (Lawesson's Reagent), 1, has been tested as a coupling reagent for racemization in peptide synthesis.The assay procedure is separation of stereomeric products by HPLC.Z-S-Pro-S-Val-S-Pro-OtBu and Z-S-Leu-S-Phe-S-Val-OtBu have been used as test peptides in 2+1 segment couplings, and only a small amount of epimerization (0.5 and 0.1percent, respectively) has been observed.