75933-82-3

Upstream product

• 77181-81-8 4-chlorophenyl 5-chloro-8-quinolyl phosphorotetrazolide 
• 71933-62-5 5'-O-(dimethoxytrityl)-2'-O-(tetrahydropyranyl)-N²-benzoylguanosine 
• 77181-80-7 Phosphorochloridic acid 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester 
• 772-79-2 4-chlorophenylphosphorodichloridate 
• 130-16-5 5-Chloro-8-hydroxyquinoline 
• 81366-72-5 4-chlorophenyl 5-chloro-8-quinolyl hydrogen phosphate 

Downstream Products

• 76951-75-2 C₈₃H₇₁ClN₁₁O₁₈P 
• 78481-24-0 Phosphoric acid (2R,3R,4R,5R)-5-(2-benzoylamino-6-oxo-1,6-dihydro-purin-9-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 5-chloro-quinolin-8-yl ester; compound with pyridine 
• 75933-86-7 Phosphoric acid (2R,3R,4R,5R)-5-(2-benzoylamino-6-oxo-1,6-dihydro-purin-9-yl)-2-hydroxymethyl-4-(tetrahydro-pyran-2-yloxy)-tetrahydro-furan-3-yl ester 4-chloro-phenyl ester 5-chloro-quinolin-8-yl ester 

Relevant academic research and scientific papers

4-CHLOROPHENYL 5-CHLORO-8-QUINOLYL HYDROGEN PHOSPHATE: A USEFUL PHOSPHORYLATING AGENT FOR GUANOSINE 3'-PHOSPHOTRIESTER

5'-O-Dimethoxytrityl-2'-O-tetrahydropyranyl-N2-benzoylguanosine smoothly reacts with 4-chlorophenyl 5-chloro-8-quinolyl hydrogen phosphate in the presence of 8-quinolinesulfonyltetrazolide (QS-te) to give 5'-O-dimethoxytrityl-2'-O-tetrahydropyr

(8-Quinolinesulfonyl)tetrazole: A New Type of Highly Efficient Coupling Agent for the Synthesis of Ribooligonucleotides by the Phosphortriester Approach

(8-Quinolinesulfonyl)Tetrazole (QS-tet) has been developed as a new type of highly efficient coupling agent in the synthesis of phosphotriester bonds.This reagent very rapidly completes the coupling reactions, and the yield is considerably higher than tha

4-CHLOROPHENYL 5-CHLORO-8-QUINOLYL PHOSPHOROCHLORIDATE: A PRACTICALLY USEFUL PHOSPHORYLATING AGENT FOR OLIGORIBONUCLEOTIDE SYNTHESIS VIA PHOSPHOTRIESTER APPROACH

5'-O-Dimethoxytrityl-2'-O-tetrahydropyranylnucleosides (2) smoothly reacts with 4-chlorophenyl 5-chloro-8-quinolyl phosphorochloridate (1) prepared form 4-chlorophenyl phosphodichloridate and 5-chloro-8-hydroxyquinoline to give 5'-O-dimethoxytrityl-2'-O-tetrahydropyranylnucleoside 3'-(4-chlorophenyl, 5-chloro-8-quinolyl) phosphates (3) in high yields.They are key intermediates for the synthesis of oligoribonucleotides via phosphotriester approach.

4-CHLOROPHENYL 5-CHLORO-8-QUINOLYL PHOSPHOROTETRAZOLIDE: A HIGHLY EFFICIENT PHOSPHORYLATING AGENT FOR OLIGORIBONUCLEOTIDE SYNTHESIS

4-Chlorophenyl 5-chloro-8-quinolyl phosphorotetrazolide (2) was a highly efficient phosphorylating agent for the synthesis of 5'-O-dimethoxytrityl-2'-O-tetrahydropyranylnucleoside 3'-(4-chlorophenyl, 5-chloro-8-quinolyl) phosphates (4).The fully protected