7597-22-0 Usage
General Description
2-Chloro-4,6-dimorpholin-4-yl-1,3,5-triazine is a chemical compound with the molecular formula C9H15ClN6O2. It consists of a triazine ring, which is a type of nitrogen-containing heterocycle, substituted by two morpholine rings and a chlorine atom. Morpholine rings are six-membered rings containing four carbon atoms, one nitrogen atom, and one oxygen atom. 2-Chloro-4,6-dimorpholin-4-yl-1,3,5-triazine could be potentially used in organic synthesis. However, specific information about its properties such as its toxicity, reactivity, and uses in various applications is not widely available or researched, showing the need for further scientific investigations.
Check Digit Verification of cas no
The CAS Registry Mumber 7597-22-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,5,9 and 7 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7597-22:
(6*7)+(5*5)+(4*9)+(3*7)+(2*2)+(1*2)=130
130 % 10 = 0
So 7597-22-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H16ClN5O2/c12-9-13-10(16-1-5-18-6-2-16)15-11(14-9)17-3-7-19-8-4-17/h1-8H2
7597-22-0Relevant articles and documents
Discovery of ortho-carborane-conjugated triazines as selective topoisomerase I/II inhibitors
Nakamura, Hiroyuki,Shoji, Atsushi,Takeuchi, Ayano,Ban, Hyun Seung,Lee, Jong-Dae,Yamori, Takao,Kang, Sang Ook
scheme or table, p. 1430 - 1437 (2012/02/06)
The cell growth inhibition profile of 2,4-(2-methyl-ortho-carboranyl)-4- (dimethylamino)-1,3,5-triazine (TAZ-6) was found to be similar to that of ICRF-193, a topoisomerase II inhibitor, as revealed by COMPARE analysis (correlation coefficient (r)≤0.724). Various mono-and di-ortho-carborane- substituted 1,3,5-triazines were synthesized based on the structure of TAZ-6 and tested for their ability to inhibit cell growth and the activities of topoisomerases I and II. Among the compounds synthesized, 3c, 4c, and 4f completely inhibited topoisomerase I activity without affecting topoisomerase II activity, whereas 3a and 3d completely inhibited topoisomerase II activity without affecting topoisomerase I activity, at 100μM.