75995-61-8

Basic information

• Product Name: cis-1,4-dibenzyl-3,6-dimethyl-2,5-dioxopiperazine
• CAS NO: 75995-61-8
• Molecular Weight: 322.407
• Mol File: 75995-61-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: cis-1,4-dibenzyl-3,6-dimethyl-2,5-dioxopiperazine(CAS DataBase Reference)
• NIST Chemistry Reference: cis-1,4-dibenzyl-3,6-dimethyl-2,5-dioxopiperazine(75995-61-8)
• EPA Substance Registry System: cis-1,4-dibenzyl-3,6-dimethyl-2,5-dioxopiperazine(75995-61-8)

Safety Data

• Hazardous Substances Data: 75995-61-8(Hazardous Substances Data)

Upstream product

• 6653-71-0 N-benzyl-2-bromopropanamide 
• 124-41-4 sodium methylate 
• 5625-46-7 cyclo(-DL-Ala-DL-Ala-) 

Downstream Products

• 7585-47-9 N-benzylalanine 

Relevant articles and documents

BASE-PROMOTED CYCLOCOUPLING REACTION OF 2-BROMOPROPANAMIDES AND 2-BROMOACETAMIDES WITH DMF

In the presence of a suitable base, representative 2-bromopropanamides 4 and 2-bromoacetamides 5 undergo cyclocondensation onto the carbonyl group of DMF to yield the 2-(dimethylamino)oxazolidin-4-ones 6 and 10, respectively.Of these cyclic orthoester ami

Base-catalysed reactions of α-bromo-N-benzyl-propionamide and -isobutyramide. Formation of 2-amino-oxazolidinones

α-Bromo-N-benzyl-propionamide and -isobutyramide react with sodium hydride yielding 2-amino-oxazolidinones. Dioxopiperazines are formed only from the halogeno-propionamide. The structure and stereochemistry of a 2-amino-oxazolidinone have been demonstrated by an X-ray crystal analysis. A cycloaddition onto an amide carbonyl is suggested in order to explain the formation of the oxazolidinone derivatives.