75996-93-9

Upstream product

• 75996-86-0 2-n-butoxycarbonylmethyl-1-methylindole-3-carboxylic acid 
• 75996-87-1 n-butyl 1-methylindol-2-ylacetate 
• 75996-85-9 2-ethoxycarbonylmethyl-1-methylindole-3-carboxylic acid 
• 57666-10-1 1-methyl-1H-indole-2-acetic acid ethyl ester 
• 75996-84-8 methyl 2-(2-methoxy-2-oxoethyl)-1-methyl-1H-indole-3-carboxylate 
• 57949-76-5 3-carboxy-1-methyl-1H-indole-2-acetic acid 
• 57949-80-1 (3-carboxy-1-methylindol-2-yl)acetic acid anhydride 
• 57666-13-4 2-(1-methyl-1H-indol-2-yl)ethan-1-ol 
• 4547-68-6 p-chlorobenzenesulfonyl azide 

Relevant academic research and scientific papers

Reactions of 4,5-Dihydro-5-methylpyranoindole-1,3-dione; a Synthesis of N-Methylisotryptophol

Boiling 4,5-dihydro-5-methylpyranoindole-1,3-dione (7) with alcohols followed by decarboxylation of the half-esters so formed leads to esters of 1-methylindol-2-ylacetic acid; reduction of these esters then affords N-methylisotryptophol (10).Reaction of 3-carboxy-1-methylindol-2-ylacetic acid (6; R=H) with acetic acid-sodium acetate gives 3,5-dimethylpyranoindol-1(5H)-one (17); with dimethylformamide-phosphorus oxychloride, 4-(NN-dimethylaminomethylene)-4,5-dihydro-5-methylpyranoindole-1,3-dione (22) was obtained.