76006-10-5

Basic information

• Product Name: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE
• Synonyms: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE;1H-Pyrazolo[3,4-c]pyridine, 7-Methoxy-;7-Methoxy-1H-pyrazolo[3
• CAS NO: 76006-10-5
• Molecular Formula: C₇H₇N₃O
• Molecular Weight: 149.152
• Mol File: 76006-10-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE(76006-10-5)
• EPA Substance Registry System: 7-METHOXY-1H-PYRAZOLO[3,4-C]PYRIDINE(76006-10-5)

Safety Data

• Hazardous Substances Data: 76006-10-5(Hazardous Substances Data)

Usage

General Description

7-Methoxy-1H-pyrazolo[3,4-c] pyridine is a chemical compound often used in scientific research and development. Notably, it falls under the class of compounds known as diazines which contain two nitrogen atoms in a six-membered aromatic ring. This chemical is distinguished by features including a methoxy group, which is a functional group composed of a methyl group bonded to an oxygen atom, and a pyrazoline ring, a type of unsaturated ring that contains nitrogen atoms. It is primarily synthesized for use in numerous areas of chemical research and can be part of various chemical reactions to produce different compounds, based on the specifics of the laboratory procedures and conditions to which it is subjected.

Upstream product

• 133627-45-9 3-Amino-2-chloro-4-methylpyridine 
• 76005-99-7 2-methoxy-3-amino-4-methylpyridine 
• 76005-98-6 3-acetamido-2-methoxy-4-methylpyridine 

Downstream Products

• 76006-25-2 7-anilino-1H-pyrazolo<3,4-c>pyridine 
• 76006-11-6 7-chloro-1H-pyrazolo<3,4-c>pyridine 
• 76006-09-2 1H-pyrazolo<3,4-c>pyridin-7(6H)-one 

Relevant articles and documents

A pyrazolopyridine compound and method for preparing the same

The invention relates to a pyrazolopyridine compound and a preparation method thereof. The compound is 3-bromo-1H-pyrazolo[3,4-c]pyridine-7(6H)-one, and the preparation method comprises the following steps: (1) by taking the compound 1 2-chloro-3-amino-4methylpyridine as a starting raw material, etherifying 2-chloro-3-amino-4methylpyridine through sodium methoxide under the catalysis of copper iodide; (2) closing pyrazole ring through isoamyl nitrite; (3) feeding pyrazol-3 through NBS (N-Bromosuccinimide); (4) removing methoxyl to obtain phenyl (mixture difficult to separate) through pyridine hydrochloride; (5) performing acetyl protection to the obtained mixture so as to separate and purify; and (6) deacetylating through using potassium carbonate as a base to obtain a final product; and according to the preparation method, the mixture difficult to purify in the reaction process is conveniently separated and purified by adopting a method of performing protection and then removing protection, and the purification difficulty caused by instability of an intermediate product can be solved.

Pyrazolopyridines. Part 5. Preparation and Reactions of Pyrazolopyridines

A series of pyrazolopyridines has been prepared by nitrosation of 3-acetamido-4-methylpyridines and subsequent rearrangement and cyclisation of the N-acetyl-N-nitroso-compounds produced.The reactions of the pyrazolopyridines have been investigated. 1- and 2-Acetyl and 1- and 2-benzyl compounds were obtained and their structures elucidated spectroscopically.The ring system readily undergoes electrophilic substitution in the 3-position. 7-Chloropyrazolopyridine has been shown to be more susceptible to nucleophilic substitution than the isomeric 5-chloro-compound.