76051-72-4

Upstream product

• 253-82-7 quinazoline 
• 7677-24-9 trimethylsilyl cyanide 
• 98-88-4 benzoyl chloride 
• 92736-32-8 3-benzoyl-3,4-dihydro-4-quinazolinecarbonitrile 
• 104548-10-9 4-cyano-3-(4-chlorobutyryl)-3,4-dihydroquinazoline 

Downstream Products

• 1459-20-7 1,2-diphenyl-2-oxoethyl benzoate 
• 95113-40-9 α-phenyl-4-quinazolinylmethyl benzoate 
• 36082-71-0 quinazoline-4-carbonitrile 
• 126994-75-0 1,3-dibenzoyl-2,4-dicyano-4-ethyl-1,2,3,4-tetrahydroquinazoline 
• 700-46-9 4-methylquinazoline 
• 55276-35-2 phenyl(quinazolin-4-yl)methanone 
• 126994-71-6 1,3-dibenzoyl-2,4-dicyano-4-methyl-1,2,3,4-tetrahydroquinazoline 
• 76051-74-6 1,3-Dibenzoyl-2-methyl-1,2,3,4-tetrahydro-quinazoline-2,4-dicarbonitrile 

Relevant academic research and scientific papers

Reissert Compound Studies. LXI. Preparation and Reactions of Quinazoline Di-Reissert Compounds

Various di-Reissert compounds and analogs were prepared from quinazoline by use of trimethylsilyl cyanide together with a catalytic amount of anhydrous aluminum chloride.Reactions of these quinazoline di-Reissert compounds are reported.

Preparation and Reactions of Mono-Reissert Compounds and Analogs at the 3,4-Position of Quinazoline

Quinazoline, acid chlorides, and trimethylsilyl cyanide have been converted to mono-Reissert compounds at the 3,4-position of the quinazoline system.Various reactions of these quinazoline Reissert compounds are reported.

Reissert Compound Studies. XXXVII. Attempts to Form Reissert Compounds From Quinazoline and Cinnoline

Reaction of quinazoline with trimethylsilyl cyanide and benzoyl chloride gave 2,4-dicyano-1,3-dibenzoyl-1,2,3,4-tetrahydroquinazoline as the major product.This compound undergoes monoalkylation with methyl iodide in the presence of sodium hydride.Reaction of cinnoline with trimethylsilyl cyanide and benzoyl chloride gave 1,2-dibenzoyl-4-cyano-1,2-dihydrocinnoline.