76088-41-0Relevant academic research and scientific papers
An efficient rapid synthesis of benzoxazoles and benzothiazoles using pma.Sio2 at room temperature under heterogeneous conditions
Sudhakar, Chithaluri,Shekhar, Vanam,Shyamsunder, Manchi,Suryakumari, Adurthi,Manojkumar, Vala
, p. 583 - 587 (2021/09/30)
Treatment of 2-aminophenol (or 2-aminothiophenol) with aromatic aldehydes in the presence of phosphomolybdic acid on silica at room temperature affords the corresponding benzoxazoles (or benzothiazoles) in excellent yields (88-96%) under heterogeneous conditions. Benzoxazoles and benzothiazoles are formed in less than 10 min.
Sulfur-Promoted Synthesis of Benzoxazoles from 2-Aminophenols and Aldehydes
Nguyen, Le Anh,Dang, Thai Duy,Ngo, Quoc Anh,Nguyen, Thanh Binh
supporting information, p. 3818 - 3821 (2020/06/10)
Elemental sulfur (S8) was found to be an excellent stoichiometric oxidant to promote oxidative condensation of 2-aminophenols with a wide range of aldehydes, including aliphatic aldehyde such as cyclohexanecarboxaldehyde. The reactions were catalyzed by sodium sulfide in the presence of DMSO as an additive. The benzoxazole products were obtained in satisfactory yields. The reaction conditions could be applied to larger syntheses (10–50 mmol).
Copper(II)-diaminosarcophagine-functionalized SBA-15: A heterogeneous nanocatalyst for the synthesis of benzimidazole, benzoxazole and benzothiazole derivatives under solvent-free conditions
Bardajee, Ghasem Rezanejade,Mohammadi, Marzieh,Kakavand, Nahale
, p. 51 - 58 (2016/04/05)
Solvent-free organic reactions were studied over periodic mesoporous silica (SBA-15) containing a Cu(II) organometallic complex. This heterogeneous catalyst was achieved by coordination of Cu(II) ions with the diaminosarcophagine ligand and then its grafting onto the surface of SBA-15. This catalyst displayed ordered mesoporous channels, which implies an extremely high dispersion of the Cu(II) complex and the convenient diffusion of reactant molecules into the pore channels. Therefore, this catalyst can offer high activity and also facile separation or recycling when compared with its homogeneous counterparts.
Simple and efficient protocol for the synthesis of benzoxazole, benzoimidazole and benzothiazole heterocycles using Fe(III)–Schiff base/SBA-15 as a nanocatalyst
Bardajee, Ghasem Rezanejade,Mohammadi, Marzieh,Yari, Hasan,Ghaedi, Aseyeh
, p. 265 - 270 (2018/03/22)
Benzimidazoles, benzoxazoles, and benzothiazoles derivatives were synthesized from condensation of aldehydes and 1,2-phenylenediamine or ortho-aminophenol or ortho-aminothiophenol in the presence of catalytic amount of Fe(III)–Schiff base/SBA-15 in water
Palladium-catalyzed intra-and intermolecular C-H arylation using mesylates: Synthetic scope and mechanistic studies
Ferguson, Devin M.,Rudolph, Stacey R.,Kalyani, Dipannita
, p. 2395 - 2401 (2014/07/21)
This paper describes the development of Pd-catalyzed inter-and intramolecular direct arylation using mesylates. Furthermore, a sequential mesylation/arylation protocol using phenols as substrates is described. These transformations are general with respect to the electronics of the C-H substrates and allow for the synthesis of diverse heterocyclic motifs in good yields. Both arenes and heteroarenes efficiently participate in these reactions. Preliminary mechanistic studies are presented for both inter-and intramolecular arylations.
Microwave-assisted one-pot synthesis of benzothiazole and benzoxazole libraries as analgesic agents
Praveen,Nandakumar,Dheenkumar,Muralidharan,Perumal
experimental part, p. 609 - 624 (2012/08/28)
Microwave-assisted synthesis of benzothiazole and benzoxazole libraries via PIFA promoted cyclocondensation of 2-aminothiophenols/2-aminophenols with aldehydes under one-pot condition in good to excellent yields was achieved. Twenty compounds have been investigated for their analgesic activity and showed moderate to good activity. Indian Academy of Sciences.
Palladium-catalyzed direct arylations, alkenylations, and benzylations through C-H bond cleavages with sulfamates or phosphates as electrophiles
Ackermann, Lutz,Barfuesser, Sebastian,Pospech, Jola
supporting information; experimental part, p. 724 - 726 (2010/04/02)
(Figure Presented) catalytic system comprised of Pd(OAc)2 and bldentate ligand dppe enabled first direct arylatlons with moisture-stable aryl sulfamates as electrophlles, and proved applicable to unprecedented C-H bond functlonallzations with e
Cu-Nanoparticles: efficient catalysts for the oxidative cyclization of Schiffs' bases
Kidwai, Mazaahir,Bansal, Vikas,Saxena, Amit,Aerry, Swati,Mozumdar, Subho
, p. 8049 - 8053 (2007/10/03)
Cu-Nanoparticles provide an efficient catalysis for the synthesis of 2-arylbenzoxazoles by the coupling of aromatic or heteroaromatic aldehydes with 2-aminophenol though the oxidative cyclization of the Schiffs' bases using 10 mol % of the Cu-nanoparticles in the presence of K2CO3 in MeOH. This method avoids the use of metal oxide or organic oxidizing agents, namely, DDQ or strong acids such as polyphosphoric acid or boric acid.
