760945-91-3Relevant academic research and scientific papers
Novel atypical antipsychotic agents: Rational design, an efficient palladium-catalyzed route, and pharmacological studies
Campiani, Giuseppe,Butini, Stefania,Fattorusso, Caterina,Trotta, Francesco,Gemma, Sandra,Catalanotti, Bruno,Nacci, Vito,Fiorini, Isabella,Cagnotto, Alfredo,Mereghetti, Ilario,Mennini, Tiziana,Minetti, Patrizia,Di Cesare, M. Assunta,Stasi, M. Antonietta,Di Serio, Stefano,Ghirardi, Orlando,Tinti, Ornella,Carminati, Paolo
, p. 1705 - 1708 (2007/10/03)
Using rational drug design to develop atypical antipsychotic drug candidates, we generated novel and metabolically stable pyrrolobenzazepines with an optimized pKi 5-HT2A/O2 ratio. 5a, obtained by a new palladium-catalyzed
COMPOUNDS WITH ATYPICAL ANTIPSYCHOTIC ACTIVITY
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Page/Page column 13, (2010/02/14)
Formula (I) compounds with atypical antipsychotic activity where the meanings of the various groups are as described here below, are endowed with activity characteristic of atypical antipsychotic agents, and therefore are useful as medicaments, particular
