76104-57-9Relevant academic research and scientific papers
Optimized 4,5-diarylimidazoles as potent/selective inhibitors of Protein Kinase CK1δ and their structural relation to P38α MAPK
Halekotte, Jakob,Witt, Lydia,Ianes, Chiara,Krüger, Marc,Bührmann, Mike,Rauh, Daniel,Pichlo, Christian,Brunstein, Elena,Luxenburger, Andreas,Baumann, Ulrich,Knippschild, Uwe,Bischof, Joachim,Peifer, Christian,Koch, Pierre,Laufer, Stefan
, (2017/04/03)
The involvement of protein kinase CK1δ in the pathogenesis of severe disorders such as Alzheimer's disease, amyotrophic lateral sclerosis, familial advanced sleep phase syndrome, and cancer has dramatically increased interest in the development of effecti
AMINE COMPOUND AND PHARMACEUTICAL USE THEREOF
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Page/Page column 60-61, (2010/04/25)
Provided is a novel amine compound represented by the following formula (I) having a superior peripheral blood lymphocyte decreasing action and superior in the immunosuppressive action, rejection suppressive action and the like, which shows decreased side effects of, for example, bradycardia and the like, or a pharmaceutically acceptable acid addition salt thereof, or a hydrate thereof, or a solvate thereof. wherein each symbol is as defined in the specification.
Single step transformation of PMB ethers to bromides using a CBr4-TPP reagent system
Yadav,Mishra, Rajesh Kumar
, p. 5419 - 5422 (2007/10/03)
PMB ethers are efficiently transformed to their corresponding bromides by a CBr4-TPP reagent system with a wide range of other functional groups also present in the substrate.
Synthesis of C-alkylcalix[4]arenes, 6. - The interaction of resorcin[4]arenes with Fe(III) in chloroform
Botta, Bruno,Delle Monache, Giuliano,Ricciardi, Paola,Zappia, Giovanni,Seri, Catia,Gacs-Baitz, Eszter,Csokasi, Pal,Misiti, Domenico
, p. 841 - 847 (2007/10/03)
Resorcinarene octamethyl ethers, bearing carboalkyloxy groups in the side chains, have been shown to interact with Fe(III) in organic media. 1H- NMR studies, carried out using Ga(III) instead of Fe(III), suggest that these systems have two active sites of interaction, the first located at the aromatic moiet and the other in the vicinity of the carbonyl groups. As a confirmation of this, resorcinarenes without carbonyl groups in the side chains have been found to exhibit only one active site. Notably, in the latter case the interaction results in configurational changes.
