22174-29-4 Usage
Uses
Used in Pharmaceutical Industry:
3-(2,4-Dimethoxyphenyl)propionic Acid is used as a synthetic reagent for the preparation of acylaminopyridinylimidazoles, which are known as p38 MAP kinase inhibitors. These inhibitors play a crucial role in the development of drugs targeting various diseases, including inflammatory conditions and certain types of cancer. The compound's unique structure allows for the efficient synthesis of these inhibitors, contributing to the advancement of pharmaceutical research and drug development.
Check Digit Verification of cas no
The CAS Registry Mumber 22174-29-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,2,1,7 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 22174-29:
(7*2)+(6*2)+(5*1)+(4*7)+(3*4)+(2*2)+(1*9)=84
84 % 10 = 4
So 22174-29-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H14O4/c1-14-9-5-3-8(4-6-11(12)13)10(7-9)15-2/h3,5,7H,4,6H2,1-2H3,(H,12,13)
22174-29-4Relevant academic research and scientific papers
p-Toluenesulfonic acid mediated hydroarylation of cinnamic acids with anisoles and phenols under metal and solvent-free conditions
Jagdale, Arun R.,Sudalai, Arumugam
, p. 4895 - 4898 (2008/02/08)
Hydroarylation of cinnamic acids with anisoles and phenols mediated by p-toluenesulfonic acid (p-TSA) under metal and solvent-free conditions gave 3-(4-methoxyphenyl)-3-phenylpropanoic acids and dihydrocoumarins, respectively, in high yields and excellent selectivity.
Hydroxyl-Directed Regioselective Monodemethylation of Polymethoxyarenes
Lal, Kasturi,Ghosh, Subrata,Salomon, Robert G.
, p. 1072 - 1078 (2007/10/02)
Methoxyl groups ortho to β-hydroxyethyl or γ-hydroxypropyl substituents in polymethoxybenzene derivatives were regioselectively demethylated with sodium thioethoxide in N,N-dimethylformamide.Methoxydihydrobenzofurans or methoxychromans were produced by cyclization of the monodemethylated β-hydroxyethyl or γ-hydroxypropyl derivatives, respectively.
