76138-82-4

Upstream product

• 59830-47-6 1-((Z)-4-Chloro-2-methyl-but-2-ene-1-sulfonyl)-4-methyl-benzene 
• 59830-48-7 (2E)-1-p-toluenesulfonyl-2-methyl-4-chloride-2-butene 
• 115125-75-2 (E)-1-iodo-3-methyl-4-tosylbut-2-ene 
• 78-79-5 isoprene 
• 98-59-9 p-toluenesulfonyl chloride 
• 824-79-3 sodium 4-methylbenzenesulfinate 

Relevant academic research and scientific papers

Synthesis of Allyl and Dienyl Sulphones via Iodosulphonylation of Conjugated Dienes

The iodosulphonylation of conjugated dienes with sodium or mercury(II) toluene-p-sulphinate and iodine yields δ-iodoalkenyl sulphones stereoselectively.These compounds undergo stereospecific dehydrohalogenation to afford dienyl sulphones and nucleophilic

ISOPRENE FUNCTIONALIZATION E/Z-ISOMERISM OF 1-SULFONYL SUBSTITUTED 2-METHYLBUTADIENES

The isomeric chlorosulfones 3, 4 and 4 are prepared by 1,4-addition of sulfonyl chlorides to isoprene.Dehydrohalogenation affords the corresponding 2- and 3-methylbutadienyl sulfones in a configuration which is dependent on the configuration of the chlorosulfone.Pure Z-2-methylbutadienyl sulfones 1 are obtained by displacement of primary halides by the Z-sulfinate anion 2.The Z-sulfones 1 are isomerized to E/Z-mixtures.The E/Z-mixtures are separated into their components and the configuration of the isomers is established by the NMR-NOE technique.