7614-96-2

Basic information

• Product Name: Phenol, 2,4,6-trinitro-, acetate (ester)
• CAS NO: 7614-96-2
• Molecular Formula: C8H5N3O8
• Molecular Weight: 271.143
• Mol File: 7614-96-2.mol

Chemical Properties

• CAS DataBase Reference: Phenol, 2,4,6-trinitro-, acetate (ester)(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2,4,6-trinitro-, acetate (ester)(7614-96-2)
• EPA Substance Registry System: Phenol, 2,4,6-trinitro-, acetate (ester)(7614-96-2)

Safety Data

• Hazardous Substances Data: 7614-96-2(Hazardous Substances Data)

Upstream product

• 88-88-0 2,4,6-trinitrochlorobenzene 
• 127-09-3 sodium acetate 
• 108-24-7 acetic anhydride 
• 88-89-1 2,4,6-Trinitrophenol 
• 71-50-1 acetate 
• 573-83-1 potassium picrate 
• 75-36-5 acetyl chloride 

Downstream Products

• 14798-26-6 picrate anion 
• 88-89-1 2,4,6-Trinitrophenol 
• 618-42-8 1-piperidin-1-yl-ethanone 
• 1696-20-4 4-acetylmorpholine 
• 13889-98-0 N-acetylpiperidine 

Relevant articles and documents

Copper(II) Tetrafluoroborate-Catalyzed Acetylation of Phenols, Thiols, Alcohols, and Amines

Copper(II) tetrafluoroborate efficiently catalyzes acetylation of structurally diverse phenols, alcohols, thiols, and amines with stoichiometric amounts of Ac2O under solvent-free conditions at room temperature. Acid-sensitive alcohols are smoothly acetylated without competitive side reactions. The reaction is influenced by the steric and electronic factors associated with the substrate as well as the anhydride. Acetylation of a sterically hindered substrate requires excess of anhydride and longer time. Acylation with less electrophilic anhydrides affords poor to moderate yields.

IMIDAZOLE DERIVATIVES CONTAINING POTENTIALLY LABILE GROUPS ON THE N(1) ATOM 8. SYNTHESIS OF N-AMINOIMIDAZOLES VIA 1-AMINO-3-METHOXYMETHYLIMIDAZOLIUM AND 1-AMINO-3-ACETYLIMIDAZOLIUM SALTS

When O-picrylhydroxylamine is reacted with 1-methoxymethyl and 1-acetyl derivatives of imidazole, benzimidazole, 2-cyanomethylbenzimidazole, and perimidine, 1-amino-3-R-imidazolium-, -benzimidazolium, and -perimidinium picrates are formed (R = CH3OCH2, CH3CO).Their subsequent hydrolysis (spontaneous in the case of the N-acetyl derivatives) results in the elimination of the labile R substituent and the formation of the corresponding N-amino-imidazole or -perimidine.In a number of cases this is a more convenient method for their synthesis than the direct amination of NH-heterocycles in alkaline medium.

Nucleophilic Reactivity: Nucleophilic Aromatic Substitution Reactions of 2,4-Dinitrochlorobenzene and Picryl Chloride in Aqueous and Methanol Solutions

Rate constants for nucleophilic aromatic substitution reactions of picryl chloride, I, with acetate ion and a series of amine nucleophiles, including primary, secondary, tertiary (quinuclidines), and amines which show the α-effect, in aqueous and methanol

REACTION OF METHYL AND PHENYL PICRATES WITH NUCLEOPHILES

The reactions of 2,4,6-trinitroanisole with various nucleophiles Me3SnM, Me3SiLi, BuLi, Me4NBBu4, PhMgI, CN-, lithium (potassium) succinimide, F-, Cl-, Br-, SCN-, NO2-, NO3-, HCO3-, PhSO2-,AcO-, S2- were investigated.It was found that the final products are the picrate and the corresponding methyl derivatives.The formation of intermediate ? complexes was detected in a series of the reactions (Me3SnLi, potassium succinimide, Bu4B-, CN-, NO2-, PhSO2-).Possible mechanisms for the reaction are examined.Reactions of 2,4,6-tricyanoanisole and phenyl picrate with certain nucleophiles were also investigated.