761414-68-0 Usage
General Description
1H-Pyrazole-5-carbonitrile, 1-(chloroacetyl)-4,5-dihydro- (9CI) is a chemical compound with the molecular formula C7H7ClN4. It is a derivative of pyrazole and is commonly used in organic synthesis and pharmaceutical research due to its potential biological activities. 1H-Pyrazole-5-carbonitrile, 1-(chloroacetyl)-4,5-dihydro- (9CI) is a chloroacetyl derivative of 5-amino-1H-pyrazole-4-carbonitrile and is known for its application in the synthesis of diverse chemical structures. Its properties and uses make it a valuable tool in drug discovery and development, as well as in the creation of new materials and compounds for various industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 761414-68-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,1,4,1 and 4 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 761414-68:
(8*7)+(7*6)+(6*1)+(5*4)+(4*1)+(3*4)+(2*6)+(1*8)=160
160 % 10 = 0
So 761414-68-0 is a valid CAS Registry Number.
761414-68-0Relevant academic research and scientific papers
Synthesis and DP-IV inhibition of cyano-pyrazoline derivatives as potent anti-diabetic agents
Ahn, Jin Hee,Kim, Hye-Min,Jung, Sun Ho,Kang, Seung Kyu,Kim, Kwang Rok,Rhee, Sang Dal,Yang, Sung-Don,Cheon, Hyae Gyeong,Kim, Sung Soo
, p. 4461 - 4465 (2007/10/03)
A new series of cyano-pyrazoline derivatives with secondary amine at P-2 site was synthesized through achiral and chiral synthetic methods and evaluated for their ability to inhibit dipeptidyl peptidase IV (DP-IV). Compound 5i revealed good in vivo efficacy (ED50: 4.1mg/kg; in vivo DP-IV inhibition). Also chiral derivative (11b) having (S)-configuration of compound 5i was found to be more potent.
