76142-16-0

Upstream product

• 76142-13-7 1-(2'-hydroxy-4',6'-dimethoxy-3',5'-dimethylphenyl)-3-(4-methoxyphenyl)-2-propen-1-one 
• 21722-31-6 1-(2-hydroxy-4,6-dimethoxy-3,5-dimethylphenyl)ethanone 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 74805-86-0 methylophiopogonone B monomethyl ether 
• 1133109-75-7 5,7-dimethoxy-6,8-dimethyl-3-(4-methoxybenzyl)chroman-4-one 

Relevant academic research and scientific papers

First synthesis of racemic methylophiopogonanone B and its inhibitory activity of hypoxia-inducible factor-1α

Methylophiopogonanone B, a constituent of Ophiopogonis tuber, found to be a potent inhibitor of hypoxia induced factor-1 α (HIF-1 α) activity, was synthesized from 2,4,6-trihydroxy-3,5-dimethylacetophenone in 57% yield. The synthetic methylophiopogonanone

STUDIES ON THE CONSTITUENTS OF OPHIOPOGONIS TUBERS. VII. SYNTHETIC STUDIES OF HOMOISOFLAVONIDS.

Several homoisoflavonoidal compounds, namely the monomethyl ethers ((IIIb) and (IVb)) of methylophiopogonones A and B, isoophiopogonone A monomethyl ether (VIIIb) and desmethylisoophiopogonone B (IXa), which were derived from the constituents of Ophiopogo