76175-72-9Relevant academic research and scientific papers
Pyridinium N-,(2'-azinyl)aminides: Regioselective synthesis of 2- alkylaminoazines
Martínez-Barrasa, Valentín,Delgado, Francisca,Burgos, Carolina,Luis García-Navío,Luisa Izquierdo,Alvarez-Builla, Julio
, p. 2481 - 2490 (2007/10/03)
The regioselective alkylation of pyridinium-N-(2f'-azinil)aminides with alkyl halides under mild conditions is described. The alkylation, combined with a reduction of the N-N bond, allows an easy preparation of 2- alkylaminoazines. (C) 2000 Elsevier Science Ltd.
Substances with antiviral activity. XV. Preparation and antiherpes activity of alkyl- and acylamino-dihalogenated pyrimidines and pyridines
Giovanninetti,Garuti,Cavrini,Roveri,Mannini Palenzona,Sinibaldi,Fusco
, p. 879 - 886 (2007/10/02)
Some dihalo-amino-pyrimidines and -pyridines were alkylated and acylated at the amino group. The resulting twenty-four compounds were then tested for their action on Herpes simplex virus infection in human HEp-2 cell cultures. Five compounds were active and 2-benzamido-3,5-dichloropyridine [(III B); Table I] showed the highest antiviral activity.
