76220-90-1

Basic information

• Product Name: 1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-
• Synonyms: 1,3-Benzenedimethanol,2-amino-5-methyl-a,a,a',a'-tetrakis(trifluoromethyl)- (9CI); NSC 354402
• CAS NO: 76220-90-1
• Molecular Formula: C13H9 F12 N O2
• Molecular Weight: 439.1969
• Mol File: 76220-90-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-(76220-90-1)
• EPA Substance Registry System: 1,3-Benzenedimethanol,2-amino-5-methyl-a1,a1,a3,a3-tetrakis(trifluoromethyl)-(76220-90-1)

Safety Data

• Hazardous Substances Data: 76220-90-1(Hazardous Substances Data)

Usage

Appearance

Colorless, odorless liquid

Reactivity

Highly reactive and powerful acid

Applications

a. Organic synthesis
b. Catalyst in chemical reactions involving fluorinated compounds
c. Production of pharmaceuticals, agrochemicals, and specialty chemicals

Toxicity

Highly toxic

Handling

Should be handled with extreme caution

Physical state

Liquid

Solubility

Not specified in the provided material, but typically soluble in organic solvents due to its fluorous nature

Stability

Not specified in the provided material, but may be sensitive to moisture and air due to its reactivity

Safety precautions

Use appropriate personal protective equipment (PPE) and follow safety guidelines when handling this compound

Upstream product

• 76220-89-8 1,4-dihydro-8-bromo-6-methyl-2,2-dimethyl-4,4-bis(trifluoromethyl)-2H-<3,1>benzoxazine 
• 684-16-2 Hexafluoroacetone 
• 80360-40-3 6-bromo-4-methyl-2-<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline 
• 80360-42-5 1,4-dihydro-8-<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>-6-methyl-2,2-dimethyl-4,4-bis(trifluoromethyl)-2H-<3,1>benzoxazine 

Downstream Products

• 76220-91-2 4-methyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>bromobenzene 
• 80360-43-6 4-methyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>iodobenzene 

Relevant articles and documents

Tridentate Ligand Useful in Stabilizing Higher Coordination States of Nonmetallic Elements. An Aryldialkoxydifluoroperiodinane

The synthesis of amino diol 2 in several steps from amino alcohol 5 allows the incorporation of the tridentate ligand in a pentacoordinate iodine species.This tridentate ligand provides stability to a hypervalent system due to its various structural features, including the five-membered rings.As a result, difluoroperiodinane 4 is isolated when iodo diol 10 is treated with 2 equiv of bromine trifluoride.This periodinane, which is a strong oxidizing reagent, demonstrated an exceptionally low reactivity.It does, however, rapidly oxidize trimethylchlorosilane or aqueoushydrogen chloride to give chlorine.Oxidation of p-chlorophenyl sulfide by 4 gives a mixture of sulfoxide and sulfone upon hydrolysis.