76227-97-9

Basic information

• Product Name: 3-(3-Benzyloxy-phenylamino)-propionic acid ethyl ester
• CAS NO: 76227-97-9
• Molecular Weight: 299.37
• Mol File: 76227-97-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3-Benzyloxy-phenylamino)-propionic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-Benzyloxy-phenylamino)-propionic acid ethyl ester(76227-97-9)
• EPA Substance Registry System: 3-(3-Benzyloxy-phenylamino)-propionic acid ethyl ester(76227-97-9)

Safety Data

• Hazardous Substances Data: 76227-97-9(Hazardous Substances Data)

Upstream product

• 1484-26-0 3-(benzyloxy)aniline 
• 140-88-5 ethyl acrylate 

Downstream Products

• 76228-00-7 1-(3-benzyloxy-phenyl)-azetidin-2-one 
• 76228-01-8 1-(3-Hydroxy-phenyl)-azetidin-2-one 

Relevant articles and documents

Formation of 2,3-Dihydro-4(1H)-quinolones and Related Compounds via Fries-type Acid-catalysed Rearrangement of 1-Arylazetidin-2-ones

A variety of 1-arylazetidin-2-ones were treated with trifluoroacetic acid under reflux, methanesulphonic acid at 100 deg C, or conc. sulphuric acid to give the corresponding 2,3-dihydro-4(1H)-quinolones via acyl migration and N-CO fission.In the case of 1-(3-substituted phenyl)azetidin-2-ones, two positional isomeric products, 5- and 7-substituted 2,3-dihydro-4(1H)-quinolones were obtained. 4-Methyl, 4-ethoxycarbonyl, and 4-piperidin-2-yl-1-arylazetidin-2-ones and their analogues were also converted into the corresponding 2-substituted 2,3-dihydro-4(1H)-quinolones under acidic conditions.The 3-substituted 1-phenylazetidin-2-ones (36) and (37) were converted into the furoquinoline systems (38) and (40), respectively, by application of this method.