76263-73-5 Usage
Uses
Used in Medicinal Chemistry:
(3S,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-phenyl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline is used as a compound of interest in medicinal chemistry for its potential chemical and biological properties. The presence of various functional groups in its structure allows for exploration of its interactions with biological targets and its potential use in the development of new drugs.
Used in Drug Development:
In the pharmaceutical industry, (3S,3aR)-2-acetyl-8-methoxy-5-[(4-methylphenyl)sulfonyl]-3-phenyl-3,3a,4,5-tetrahydro-2H-pyrazolo[4,3-c]quinoline is used as a candidate molecule in drug development. Its unique molecular structure, including the pyrazoloquinoline backbone and the various attached groups, may offer opportunities for the design of novel therapeutic agents targeting specific diseases or conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 76263-73-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,2,6 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 76263-73:
(7*7)+(6*6)+(5*2)+(4*6)+(3*3)+(2*7)+(1*3)=145
145 % 10 = 5
So 76263-73-5 is a valid CAS Registry Number.
76263-73-5Relevant academic research and scientific papers
Studies in Antifertility Agents: Part XXVII - Synthesis of 2-Acetyl-3-aryl-5-tosyl-7/8-H (or methoxy)-3,3a,4,5-tetrahydropyrazoloquinolines
Kelkar, Prabhakar M.,Sangwan, Naresh K.,Rastogi, Shri Nivas,Anand, Nitya
, p. 297 - 300 (2007/10/02)
N-Tosyl-2,3-dihydro-4-quinolones (12-14), prepared from aniline, m- and p-anisidines by reported procedures, on condensation with araldehydes in the presence of NaOMe give the corresponding 3-arylidene-4-quinolones (15-18).Refluxing of 15-18 with NH2-NH2*H2O in gl.AcOH affords the title compounds, 2-acetyl-3-aryl-5-tosyl-7/8-H (or methoxy)-3,3a,4,5-tetrahydropyrazoloquinolines (19-22).The stereochemistry of the title compounds based on the assignments of C3-H, C3a-H, C4-H2 protons has been studied by PMR decoupling experiments.In preliminary screening, compounds 19 and 22 have been found to prevent pregnancy at 20 mg/kg dose in female albino rats, but are ineffective at lower doses.None of the compounds tested shows any significant pharmacological activity.
