76297-05-7

Usage

Type of compound

Benzoate ester

Usage

Fragrance ingredient in consumer products (perfumes, lotions, soaps)

Structure

Spiro carbon ring and a benzoate group

Property

Pleasant odor

Suitability

Cosmetic and personal care products

Safety

Use with caution and in accordance with safety guidelines

Health risks

Potential risks with excessive or prolonged exposure

Upstream product

• 22428-87-1 4,4-ethylenedioxycyclohexan-1-ol 
• 98-88-4 benzoyl chloride 
• 4746-97-8 cyclohexanedione monoethylene ketal 

Downstream Products

• 23510-95-4 4-benzoyloxycyclohexanone 
• 1342811-10-2 C₁₈H₁₈BrN₃O₂ 
• 1342811-11-3 C₁₈H₁₅BrN₂O₂ 
• 1342811-12-4 C₁₉H₁₇BrN₂O₂ 
• 1342811-15-7 C₁₉H₁₉BrN₂O₂ 
• 1342811-16-8 C₁₉H₁₆BrNO₂ 
• 1342811-17-9 C₂₀H₁₈BrNO₂ 
• 1342811-20-4 C₁₉H₁₉BrN₂O₂ 
• 1342811-21-5 7-bromo-2,3,4,9-tetrahydro-1H-carbazol-3-yl benzoate 
• 1342811-22-6 5-bromo-2,3,4,9-tetrahydro-1H-carbazol-3-yl benzoate 
• 1342811-23-7 C₂₀H₁₈BrNO₂ 

Relevant academic research and scientific papers

Facile synthesis of N-substituted amides from alkenes and amides by a Bronsted acid mediated electrophilic addition reaction

A facile and widely applicable method for the synthesis of N-substituted amides from alkenes and amides using Bronsted acids was developed. Treatment of various alkenes with amides and an alkali metal halide or methanesulfonic acid in trifluoroacetic acid afforded the corresponding N-substituted amides in good to high yield. The reaction proceeds via the direct electrophilic addition of the amides to the alkenes. Various functional groups such as ester, ether, imide, amide, and halogen were tolerated under the reaction conditions. High substrate-dependent cis stereoselectivity in the synthesis was also observed for methylenecyclohexane and methylcyclohexene derivatives possessing a substituent at the 4-position. Furthermore, a practical application of this reaction has been demonstrated by the synthesis of an intermediate of a bioactive compound on a large scale. Georg Thieme Verlag Stuttgart New York.

Novel Compounds for the Treatment of Diseases Associated with Amyloid or Amyloid-Like Proteins

The present invention relates to novel compounds that can be employed in the treatment of a group of disorders and abnormalities associated with amyloid protein, such as Alzheimer's disease, and of diseases or conditions associated with amyloid-like proteins. The compounds of the present invention can also be used in the treatment of ocular diseases associated with pathological abnormalities/changes in the tissues of the visual system. The present invention further relates to pharmaceutical compositions comprising these compounds and to the use of these compounds for the preparation of medicaments for treating or preventing diseases or conditions associated with amyloid and/or amyloid-like proteins. A method of treating or preventing diseases or conditions associated with amyloid and/or amyloid-like proteins is also disclosed.