76301-01-4

Basic information

• Product Name: Propanoic acid, 2-(trimethoxysilyl)-, methyl ester
• CAS NO: 76301-01-4
• Molecular Formula: C7H16O5Si
• Molecular Weight: 208.287
• Mol File: 76301-01-4.mol

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-(trimethoxysilyl)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-(trimethoxysilyl)-, methyl ester(76301-01-4)
• EPA Substance Registry System: Propanoic acid, 2-(trimethoxysilyl)-, methyl ester(76301-01-4)

Safety Data

• Hazardous Substances Data: 76301-01-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 2768-02-7 (vinyl)trimethoxylsilane 
• 201230-82-2 carbon monoxide 

Relevant articles and documents

The Highly Regioselective Carbonylation of Vinylsilanes

The hydroesterification of vinylsilanes, catalyzed by transition-metal complexes, afforded both β-silyl esters 2 and α-silyl esters 3 in high yield.The Pd(II) complex-catalyzed reaction showed high β-regioselectivity, whereas the Co2(CO)8-catalyzed reaction showed high α-regioselectivity.Vinylsilanes which bore trialkyl-, diphenylmethyl-, dimethylethoxy-, trimethoxy-, diphenylfluoro-, and difluorophenylsilyl groups were regioselectively, and in some cases regiospecifically, hydroesterified.Pd(II) complexes were also shown to be effective catalysts of the hydrocarboxylation of vinylsilanes.Hydrocarboxylation was β-regiospecific and gave excellent yields of β-silyl carboxylic acids.Reasonable mechanisms for the reactions are described.