76306-62-2

Basic information

• Product Name: N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>acetamide
• Synonyms: N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>acetamide
• CAS NO: 76306-62-2
• Molecular Weight: 359.422
• Mol File: 76306-62-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>acetamide(76306-62-2)
• EPA Substance Registry System: N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>acetamide(76306-62-2)

Safety Data

• Hazardous Substances Data: 76306-62-2(Hazardous Substances Data)

Upstream product

• 554-34-7 1,2-bis(3,4-dimethoxyphenyl)ethane-1,2-dione 
• 10313-60-7 3,4-dimethoxyphenylacetyl chloride 
• 6267-07-8 3,4,3',4'-tetramethoxy-deoxybenzoin oxime 
• 91-16-7 1,2-dimethoxybenzene 
• 4927-55-3 1,2-bis(3,4-dimethoxyphenyl)ethanone 
• 76306-70-2 N-<1,2-bis(3,4-dimethoxyphenyl)ethyl>formamide 
• 108-24-7 acetic anhydride 
• 5471-40-9 3,4,3',4'-tetramethoxy-bibenzyl-α-ylamine 
• 58973-47-0 2,3-bis-(3,4-dimethoxy-phenyl)-propionic acid hydrazide 

Downstream Products

• 135365-12-7 5-(3,4-Dimethoxy-phenyl)-8,9-dimethoxy-10b-methyl-6,10b-dihydro-5H-oxazolo[2,3-a]isoquinoline-2,3-dione 
• 76306-43-9 3,4-dihydro-6,7-dimethoxy-3-(3,4-dimethoxyphenyl)-1-methylisoquinoline 
• 87419-47-4 3-(3,4-Dimethoxy-phenyl)-6,7-dimethoxy-1-methyl-3,4-dihydro-isoquinoline; hydrochloride 
• 18513-98-9 3,4,3',4'-Tetramethoxystilben 
• 96756-78-4 N-<2-(2-bromo-4,5-dimethoxyphenyl)-1-(3,4-dimethoxyphenyl)ethyl>acetamide 
• 84573-13-7 (E)-1-(2-bromo-4,5-dimethoxyphenyl)-2-(3,4-dimethoxyphenyl)ethylene 
• 76306-44-0 C₁₈H₂₀Cl₂O₄ 
• 5471-40-9 3,4,3',4'-tetramethoxy-bibenzyl-α-ylamine 

Relevant articles and documents

A Modified Bischler-Napieralski Procedure for the Synthesis of 3-Aryl-3,4-dihydroisoquinolines

A modification of the Bischler-Napieralski reaction for the cyclization of (1,2-diphenylethyl)amides to the 3-aryl-3,4-dihydroisoquinolines is presented.Elimination of the amide group as the nitrile via the retro-Ritter reaction is avoided by its conversion to an N-acyliminium intermediate with oxalyl chloride-FeCl3.Removal of the oxalyl group in refluxing MeOH-sulfuric acid provides the 3,4-dihydroisoquinolines in moderate to high yields.The method is also highly effective with (2-phenylethyl)amides.