76323-08-5

Basic information

• Product Name: 1-acetyl-1,3-bis(benzoyloxy)benzene
• Synonyms: 1-acetyl-1,3-bis(benzoyloxy)benzene
• CAS NO: 76323-08-5
• Molecular Weight: 360.366
• Mol File: 76323-08-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-acetyl-1,3-bis(benzoyloxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-acetyl-1,3-bis(benzoyloxy)benzene(76323-08-5)
• EPA Substance Registry System: 1-acetyl-1,3-bis(benzoyloxy)benzene(76323-08-5)

Safety Data

• Hazardous Substances Data: 76323-08-5(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 490-78-8 2,5-Dihydroxyacetophenone 
• 699-83-2 2,6-dihydroxylacetophenone 

Downstream Products

• 76323-09-6 2,5-dihydroxydibenzyloxymethane 
• 107139-52-6 [2-(2,5-Bis-benzoyloxy-phenyl)-2-oxo-ethyl]-triphenyl-phosphonium; bromide 
• 107127-93-5 1-(2,5-Dihydroxy-phenyl)-2-(triphenyl-λ⁵-phosphanylidene)-ethanone 
• 107127-96-8 6-Hydroxy-2-(2-nitro-phenyl)-chromen-4-one 
• 35794-88-8 6‐hydroxy‐4′‐methoxyflavone 
• 22105-12-0 6-hydroxy-2-methyl-chromen-4-one 
• 89263-93-4 1-(6-benzoyloxy-2-hydroxyphenyl)-3-phenylpropane-1,3-dione 
• 6665-83-4 6-hydroxyflavone 

Relevant articles and documents

Synthesis of novel flavone acyl esters and correlation of log P value with antioxidant and antimicrobial activity

Three series of flavones namely 6-hydroxy flavone, 6-chloro-3-hydroxy flavone, 3,6-dihydroxy flavone were synthesized. They were further benzoylated with different aromatic acid chlorides in the presence of pyridine gave three of acyl esters series (SCF 1 to 8, SHF 1 to 8 and SDF 1 to 8). The yields of all the substituted flavones were found satisfactory. These compounds were purified, characterized by their spectral data. log P and pKa value. They were screened for in vitro radical (DPP?) scavenging activity, showed appreciable activity. 7 compounds showed antimicrobial activity against Gram-positive bacteria. Further, the MIC values of these 7 compounds were also determined. All the compounds showing antioxidant activity also showed antibacterial activity. The relationship between log P, antioxidant and antibacterial activity was established.