89263-93-4

Usage

Molecular weight

322.32 g/mol

Appearance

Colorless to white crystalline solid

Solubility

Soluble in organic solvents like ethanol, acetone, and diethyl ether; slightly soluble in water

Melting point

88-92°C

Boiling point

435-440°C

Density

1.25 g/cm3

Uses

a. Insecticide and acaricide for controlling pests on plants and crops
b. Treatment for scabies and lice infestations in humans and animals
c. Fragrance ingredient in perfumes
d. Flavoring agent in food and beverages
e. Studied for potential anti-inflammatory and anti-cancer properties

Safety precautions

Can be irritating to skin, eyes, and respiratory system; handle with care and use appropriate protective measures.

Upstream product

• 76323-08-5 1-acetyl-1,3-bis(benzoyloxy)benzene 
• 699-83-2 2,6-dihydroxylacetophenone 
• 98-88-4 benzoyl chloride 
• 490-78-8 2,5-Dihydroxyacetophenone 

Downstream Products

• 6665-83-4 6-hydroxyflavone 

Relevant academic research and scientific papers

An Efficient One-Pot Synthesis and Anticancer Activity of 4'-Substituted Flavonoids

A number of 4'-substituted (R = H, Me, Cl, F) flavone derivatives is synthesized from 2-hydroxyacetophenones using the modified Baker–Venkataraman reaction. Compound [3-(4-fluorobenzoyl)-5- hydroxy-4'-fluoroflavone] was synthesized for the first time with the yield of 12%. Antiproliferative assays indicate that the synthesized flavones with F substituent at the 4' position demonstrate higher activity than the other flavone derivatives, particularly against HeLa and MCF-7 with the IC50 9.5 and 2.7 μM, respectively.

Structural Studies on Bio-active Compounds. Part 12. Tautomerism and Conformation of Aryl-substituted 1-(2-Hydroxyphenyl)-3-phenylpropane-1,3-diones in the Solid Phase and in Solution

The tautomerism of a series of aryl-substituted 1-(2-hydroxyphenyl)-3-phenylpropane-1,3-diones has been studied in deuteriochloroform solution by 1H n.m.r. techniques and, in the case of 1-(2-hydroxy-4-methoxyphenyl)-3-phenylpropane-1,3-dione and 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylpropane-1,3-dione, in the solid state by X-ray crystallography.Of these compounds, most exist between 80 and 95percent in the enolised form in solution and 1-(2-hydroxy-4-methoxyphenyl)-3-phenylpropane-1,3-dione adopts this tautomer in the crystal.However, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenylpropane-1,3-dione is present as the diketone in the solid phase and enolises very slowly in solution. 1-(6-Benzoyloxy-2-hydroxyphenyl)-3-hydroxy-3-phenylprop-2-en-1-one is shown by 1H n.m.r. spectroscopy possibly to adopt a 'coiled' conformation in solution in deuteriochloroform.