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4-bromo-N-(4-bromophenyl)butanamide is an organic compound with the chemical formula C10H10Br2NO. It is a derivative of butanamide, featuring a 4-bromophenyl group attached to the nitrogen atom and bro amine atom at the 4-position of the butanamide chain. 4-bromo-N-(4-bromophenyl)butanamide is characterized by its two bromine atoms, which contribute to its reactivity and potential applications in chemical synthesis. It is a white crystalline solid and is often used as an intermediate in the production of pharmaceuticals and other organic compounds. Due to the presence of bromine atoms, it may also be involved in reactions such as halogenation or substitution, making it a versatile building block in organic chemistry.

7634-72-2

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7634-72-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 7634-72-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,6,3 and 4 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7634-72:
(6*7)+(5*6)+(4*3)+(3*4)+(2*7)+(1*2)=112
112 % 10 = 2
So 7634-72-2 is a valid CAS Registry Number.

7634-72-2Relevant academic research and scientific papers

DRUG DELIVERY SYSTEM FOR TREATING DISEASE

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Page/Page column 17; 18, (2019/05/22)

The present invention relates to HPMA-CBz copolymers and methods for treating certain diseases comprising administering the copolymers to a subject in need thereof.

Consequences of linker length alteration of the α7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333

Beinat, Corinne,Banister, Samuel D.,Van Prehn, Saundra,Doddareddy, Munikumar Reddy,Hibbs, David,Sako, Michael,Chebib, Mary,Tran, Thao,Al-Muhtasib, Nour,Xiao, Yingxian,Kassiou, Michael

supporting information; experimental part, p. 2380 - 2384 (2012/05/05)

A series of ligands based on SEN12333, containing either contracted or elongated alkyl chains, were synthesized and evaluated in molecular docking studies against a homology model of the α7 nicotinic acetylcholine receptor (nAChR) subtype. The predicted binding of all ligands was highly similar, with the exception of the analog containing a 5 methylene unit spacer. However, in vitro competition binding assays revealed that the ligands possessed dissimilar binding affinities, with a Ki range of more than an order of magnitude (Ki = 0.50 to >10 μM), and only SEN12333 itself exhibited functional activity at the α7 nAChR.

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