76350-89-5Relevant academic research and scientific papers
STYRENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS
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Page/Page column 143-144, (2008/12/08)
The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.
HIV PROTEASE INHIBITORS, COMPOSITIONS CONTAINING THE SAME AND THEIR PHARMACEUTICAL USES
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Page/Page column 100, (2010/02/11)
This invention relates to a novel series of chemical compounds useful as Human immunodeficiency Virus (HIV) protease inhibitors and to the use of such compounds as antiviral agents. The invention further relates to pharmaceutical compositions containing s
A formal synthesis of crinipellin B based on the arene-alkene meta- photocycloaddition reaction
Wender, Paul A.,Dore, Timothy M.
, p. 8589 - 8592 (2007/10/03)
Starting from triethyl phosphonopropionate and 3-nitro-2-methylbenzoic acid, a formal synthesis of crinipellin B was achieved. The strategy draws on the use of a novel version of the arene-alkene meta-photocycloaddition reaction that proceeds with the generation of 4 rings and 4 quaternary stereocenters in one synthetic operation.
Synthesis of 3--2-methylbenzoic acid a metabolite of the drug, detomidine.
Cardin, Christine J.,Convery, Maire A.,Kavanagh, Pierce V.,Lambert, Michael T. B.,McKenna, Brian,McMurry, T. Brian H.
, p. 3026 - 3038 (2007/10/02)
Detomidine (1a) is a very useful analgesic which has considerable value in equine veterinary practice.It is metabolised in the rat to give a number of derivatives, among which the alcohol (1c) and the acid (1b) are the most important.Recently, a method ha
