76385-62-1Relevant academic research and scientific papers
Synthesis, DFT and POM analyses of cytotoxicity activity of α-amidophosphonates derivatives: Identification of potential antiviral O,O-pharmacophore site
Rachedi, Khadidja Otmane,Ouk, Tan-Sothea,Bahadi, Rania,Bouzina, Abdeslem,Djouad, Seif-Eddine,Bechlem, Khaoula,Zerrouki, Rachida,Ben Hadda, Taibi,Almalki, Faisal,Berredjem, Malika
, p. 196 - 203 (2019)
In the present study, we investigated the cytotoxic activity of three compounds prepared starting from amino acids. These derivatives were evaluated for their in vitro antitumor activity against human cell lines (PRI, K562 and JURKAT). Their cytotoxicity
Inhibitors of Pyrimidine Biosynthesis. Part 1. Synthesis of Potential Transition-state Analogues of Aspartate Transcarbamylase
Goodson, John J.,Wharton, Clifford J.,Wrigglesworth, Roger
, p. 2721 - 2727 (2007/10/02)
A systematic variation of the structure of a transition-state analogue of aspartate transcarbamylase has been carried out.A new, and general, synthesis of these analogues, starting from the appropriate amino-acid is described.
