764-45-4Relevant academic research and scientific papers
Nrf2 Activating Compounds and Uses Thereof
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Paragraph 0520; 0521; 0522; 0523; 0524, (2017/08/26)
Aspects of the present disclosure include compounds that activate Nrf2. Such compounds find use in the treatment of autoimmune and inflammatory diseases and disorders, such as for example psoriasis and multiple sclerosis. Embodiments of the present disclo
Formation of symmetrical alkenes by homocoupling of metallated sulfones under nickel catalysis
Gai, Yonghua,Julia, Marc,Jean-Noe,Verpeaux
, p. 805 - 816 (2007/10/03)
Summary -Allylic sulfones undergo a coupling reaction with organometallic compounds (Mg or Li) not only with copper catalysts but also with iron or nickel salts. With 7,7-disubstituted allylic sulfones and also saturated aliphatic sulfones, however, another reaction was observed whereby two molecules of the starting sulfone are coupled to give symmetrical alkenes. The scope of this reaction was investigated. Elsevier.
Nucleophilic Substitutions of Unactivated Vinyl Halides with Alkanethiolate Anions in Hexamethylphophoramide
Tiecco, Marcello,Testaferri, Lorenzo,Tingoli, Marco,Chianelli, Donatella,Montanucci, Manuela
, p. 4795 - 4800 (2007/10/02)
The reactions of unactivated vinyl halides with the sodium salts of alkanethiols in HMPA gave vinyl alkyl sufides in high yields.These reactions occur with complete retention of configuration.With di-, tri-, and tetrachloroethylenes all the chlorine atoms are substituted by alkylthio groups.By treatment with alkanethiolates the vinyl sulfides are dealkylated to give the sodium salts of the ene thiols.By reaction with sodium all the alkylthiogroups present in the molecule suffer fragmentation to give the sodium salts of the corresponding mercaptoethylenes.
PHOTOCHEMICAL REACTIONS OF 2-BORNANETHIONE (THIOCAMPHOR) WITH BIS(METHYLTHIO)ETHYNE. ADDITION AND INTRAMOLECULAR HYDROGEN ABSTRACTION
Brouwer, A. C.,Bos, H. J. T.
, p. 103 - 109 (2007/10/02)
Irradiation of a mixture of bornanethione 7 and bis(methylthio)ethyne 2a afforded a mixture of methyl E- and Z-2-(2-bornylidene)-2-(methylthio)ethanedithioate 8 and E-1,2-bis(methylthio)vinyl 2-bornen-2-yl sulfide 10E.The first compounds are the products of the (2+2)-photocycloaddition reaction between bornanethione 7 and acetylene 2a.The sulfide 10E is rationalised as being the product of an intramolecular H abstraction reaction of the 1,4-biradical 12 which is also believed to be the intermediate in the (2+2)-cycloaddition reaction.
(E-Z) ISOMERISM OF VINYL SULFIDES AND ETHERS
Prochazka, Milos,Vondrak, Tomas,Polakova, Jana
, p. 286 - 291 (2007/10/02)
Enthalpic data for the (E-Z) isomerisation of 1-methoxy-1-propene, 1-methylthio-1-propene, 1-methoxy-2-methylthioethene and 1,2-bis(methylthio)ethene were analyzed on the basis of calculated (CNDO/2) energy differences between the isomers.
