76431-30-6

Usage

Uses

Used in Organic Synthesis:
2,2,2-Trichloroethyl [2R-[2α,3β(R)]]-1-[2-[[(ethylthio)thioxomethyl]thio]-4-oxoazetidin-3-yl]ethyl carbonate is used as a building block in organic synthesis for the creation of various complex molecules. Its unique structure and functional groups make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Chemical Reactions:
2,2,2-trichloroethyl [2R-[2alpha,3beta(R)]]-1-[2-[[(ethylthio)thioxomethyl]thio]-4-oxoazetidin-3-yl]ethyl carbonate serves as a reagent in various chemical reactions, facilitating the formation of desired products. Its presence can enhance reaction efficiency, selectivity, and yield, making it a useful tool in the development of new chemical processes and methodologies.
Used in Pharmaceutical Industry:
2,2,2-Trichloroethyl [2R-[2α,3β(R)]]-1-[2-[[(ethylthio)thioxomethyl]thio]-4-oxoazetidin-3-yl]ethyl carbonate may have potential pharmaceutical uses, although further research and testing are needed to determine its specific applications. Its unique structure and functional groups could contribute to the development of new drugs or drug candidates, particularly in the areas of medicinal chemistry and drug discovery.

Upstream product

• 35444-20-3 potassium ethyltrithiocarbonate 
• 76431-28-2 Carbonic acid 1-[1-(tert-butyl-dimethyl-silanyl)-2-ethylsulfanyl-4-oxo-azetidin-3-yl]-ethyl ester 2,2,2-trichloro-ethyl ester 
• 76431-35-1 methyl (2α,3β(R*))-2-chloro-α-(isopropylidene)-4-oxo-3-(1-{[(2,2,2-trichloroethoxy)carbonyl]oxy}ethyl)azetidine-1-acetate 
• 75-15-0 carbon disulfide 
• 54669-43-1 potassium ethanethiolate 
• 76431-36-2 methyl (2α,3β(R*))-2-chloro-α,4-dioxo-3-(1-{[(2,2,2-trichloroethoxy)carbonyl]oxy}ethyl)azetidine-1-acetate 
• 80374-82-9 methyl (3S,5R,6R)-6-<(R)-1-hydroxyethyl>penicillanate 
• 76431-29-3 Carbonic acid 1-(2-ethylsulfanyl-4-oxo-azetidin-3-yl)-ethyl ester 2,2,2-trichloro-ethyl ester 
• 76431-27-1 1-(t-butyldimethylsilyl)-3-(1-hydroxyethyl)-4-ethylthioazetidin-2-one 
• 76448-69-6 Trithiocarbonic acid 1-(tert-butyl-dimethyl-silanyl)-3-(1-hydroxy-ethyl)-4-oxo-azetidin-2-yl ester ethyl ester 
• 80629-64-7 Carbonic acid 1-[1-(tert-butyl-dimethyl-silanyl)-2-ethylsulfanylthiocarbonylsulfanyl-4-oxo-azetidin-3-yl]-ethyl ester 2,2,2-trichloro-ethyl ester 
• 76431-34-0 (2S,5R,6S)-3,3-Dimethyl-7-oxo-6-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid methyl ester 
• 80629-46-5 methyl 6-α-bromo-6-β-<(1R)-hydroxyethyl>penicillanate 
• 76581-81-2 methyl (3S,5R,6S)-6-<(R)-1-hydroxyethyl>penicillanate 

Downstream Products

• 80575-09-3 {(2R,3S)-2-Ethylsulfanylthiocarbonylsulfanyl-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 
• 80575-09-3 {(2R,3S)-2-Ethylsulfanylthiocarbonylsulfanyl-4-oxo-3-[(S)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 
• 76431-43-1 (5R,6S)-3-Ethylsulfanyl-6-((S)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester 
• 80575-09-3 {(2R,3R)-2-Ethylsulfanylthiocarbonylsulfanyl-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 
• 76431-43-1 (5R,6R)-3-Ethylsulfanyl-6-((R)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester 
• 80575-09-3 {(2R,3R)-2-Ethylsulfanylthiocarbonylsulfanyl-4-oxo-3-[(S)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 
• 76431-43-1 (5R,6R)-3-Ethylsulfanyl-6-((S)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester 
• 80575-09-3 {(2R,3S)-2-Ethylsulfanylthiocarbonylsulfanyl-4-oxo-3-[(R)-1-(2,2,2-trichloro-ethoxycarbonyloxy)-ethyl]-azetidin-1-yl}-(triphenyl-λ⁵-phosphanylidene)-acetic acid allyl ester 
• 76431-43-1 (5R,6S)-3-Ethylsulfanyl-6-((R)-1-hydroxy-ethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester 

Relevant academic research and scientific papers

SYNTHESIS OF RACEMIC, 2-(ALKYLTHIO)-6-(1-HYDROXYETHYL) PENEMS; ATTEMPTED PENEM SYNTHESIS VIA COPPER (I) - PROMOTED CYCLISATIONS

Stereocontrolled syntheses of the diastereoisomeric 6-(1-hydroxyethyl)-2-ethylthio and 2-(2-aminoethylthio)-penem-3-carboxylates from a common monocyclic azetidinone precursor are described.Cu (I)-promoted cyclisation of suitable N/C-3 secopenems is shown to yield "isopenems" (7-oxo-2-thia-1-azabicyclohept-3-enes) as the sole bicyclic product.

SYNTHESIS OF OPTICALLY ACTIVE PENEMS

A general synthesis for optically active penems is described.Penems undergo a novel thermal isomerisation reaction.