76439-45-7

Usage

Uses

Used in Organic Synthesis:
3-Chloro-4-nitropyridine N-oxide is utilized as a building block in organic synthesis for the preparation of a wide range of pharmaceuticals, agrochemicals, and other organic compounds. Its unique chemical structure allows for the creation of diverse molecules with specific therapeutic or functional properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-chloro-4-nitropyridine N-oxide is used as a key intermediate for the synthesis of various drugs. Its presence in the molecular structure can contribute to the development of new medications with improved efficacy and selectivity.
Used in Agrochemical Industry:
3-Chloro-4-nitropyridine N-oxide is also employed in the agrochemical industry for the synthesis of pesticides and other crop protection agents. Its incorporation into these compounds can enhance their effectiveness against pests and diseases, thereby improving agricultural productivity.
Used as an Anti-fungal and Anti-bacterial Agent:
3-Chloro-4-nitropyridine N-oxide has demonstrated potential as an anti-fungal and anti-bacterial agent. It can be used in the development of new antimicrobial formulations for various applications, including medical, veterinary, and industrial settings.
Used in Material Science:
In the field of material science, 3-chloro-4-nitropyridine N-oxide has been studied for its potential use in the development of novel materials with unique properties. Its chemical structure and reactivity can contribute to the creation of advanced materials for various applications, such as sensors, catalysts, and energy storage devices.
Used in the Development of Electronic and Optoelectronic Devices:
3-Chloro-4-nitropyridine N-oxide has gained significance in the development of electronic and optoelectronic devices due to its potential applications in improving device performance and functionality. Its incorporation into these devices can lead to enhanced electrical and optical properties, contributing to the advancement of technology in various sectors.

InChI:InChI=1/C5H3ClN2O3/c6-4-3-7(9)2-1-5(4)8(10)11/h1-3H

Upstream product

• 626-60-8 3-Chloropyridine 
• 1851-22-5 3-chloropyridine-N-oxide 
• 1066-33-7 ammonium bicarbonate 

Downstream Products

• 1796-73-2 4-amino-3-N-methylaminopyridine 
• 7322-04-5 3-methylimidazo<4,5-c>pyridine 
• 52538-09-7 2,3-dimethylimidazo<4,5-c>pyridine 
• 61719-62-8 N-3-ethyl-pyridine-3,4-diamine 
• 13194-60-0 3-chloro-4-nitropyridine 

Relevant academic research and scientific papers

A Journey through Hemetsberger–Knittel, Leimgruber–Batcho and Bartoli Reactions: Access to Several Hydroxy 5- and 6-Azaindoles

The preparation of various 5- and 6-azaindoles, heterocyclic structures that are frequently part of molecules in clinical development, and their monohydroxy analogues were described. Different strategies, relying on the de novo pyrrole ring formation, were investigated and, thanks to Hemetsberger–Knittel, Bartoli and Leimgruber–Batcho approaches, 4- and 7-monohydroxy 5- and 6-azaindoles were obtained. The crucial introduction of the oxygen atom was carried out from halogen derivatives, using nucleophilic substitution reactions under basic conditions with or without a copper catalyst. Some preliminary oxidation reactions have shown that it was yet not possible to synthesize the azaquinone indole structure from monohydroxy azaindole, using molecular oxygen in the presence of salcomine as a catalyst.

ANTHRANILAMIDE COMPOUNDS, PROCESS FOR PRODUCING THESE, AND PEST CONTROL AGENT COMPRISING ANY OF THESE

A novel pest control agent. Also provided are: an anthranilamide compound represented by the formula (I): (I) (wherein A is Y-substituted alkyl or D-substituted carbonyl; Q is optionally R5-substituted 3-pyridyl or optionally R5-substituted 4-pyridyl; R1 is halogeno, optionally X-substituted alkyl, etc.; R2 and R5 each is halogeno, optionally X-substituted alkyl, etc.; R3 and R4 each is hydrogen or alkyl; X is halogeno, optionally halogenated alkoxy, etc.; Y is C3-4 cycloalkyl, etc.; D is alkenyl, etc.; m is an integer of 0-4; and n is 1 or 2); an N-oxide of the compound; and a salt of the compound.

Substituted ring-fused imidazole derivative: GABAA receptors ligands

Substituted ring-fused imidazole derivatives that bind to GABAA receptors are provided. Such compounds may be used to modulate ligand binding to GABAA receptors in vivo or in vitro, and are particularly useful in the treatment of a v

Benzimidazole and pyridylimidazole derivatives

This invention relates to benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds, all of which may be described by of Formula I The invention is particularly related to such compounds that bind with high selectivity and high affinity to the benzodiazepine site of GABAA receptors. This invention also relates to pharmaceutical compositions comprising such compounds and to the use of such compounds in treatment of certain central nervous system (CNS) diseases. Novel processes for preparing compounds of Formula I are disclosed. This invention also relates to the use of benzimidazoles, pyridylimidazoles and related bicyclic heteroaryl compounds of Formula I in combination with one or more other CNS agents to potentiate the effects of the other CNS agents. Additionally this invention relates to the use such compounds as probes for the localization of GABAA receptors in tissue sections.

Cell adhesion-inhibiting antiinflammatory compounds

Compounds having Formula I are useful for treating inflammation. Also disclosed are pharmaceutical compositions comprising compounds of Formula I, and methods of inhibiting/treating inflammatory diseases in a mammal.

Chemistry of the Phenoxathiins and Isosterically Related Heterocycles. XXXII. The Synthesis of 2-Azathianthrene and Selected Analogs

The synthesis of 2-azathianthrene (benzodithiinopyridine), the only remaining monoazathianthrene yet to be reported, is described.Attempts at the direct condensation of disubstituted pyridines with the dianion of 1,2-dimercaptobenzene were generally unsuccessful requiring that the alternative condensation of the dianion with disubstituted pyridine 1-oxides be employed.The title compound was characterized by physical means including 13 C-nmr spectroscopy.One analog, 4-nitro-2-azathianthrene was also studied by X-ray crystallographic means; the molecule crystallized with two molecules in the asymetric unit P21/n, a=20.712(3), b=7.8109(13), c=13.720(2) Angstroem, β=107.880(11) deg, Z=8, the data refined to a final R=0.051 for 3061 reflections.Dihedral angles between the planes of the phenyl rings were 135.00(13) and 132.52(13) deg for the two independent molecules contained in the crystal.Close non-bonded S...O intramolecular contacts were observed in both molecules between the sulfur and nitro-group oxygens.Both nitro groups are twisted out the plane of the pyridine ring and are oriented at angles of 28.75 and 38.82 deg respectively.