7322-04-5Relevant academic research and scientific papers
Copper- and palladium-catalyzed amidation reactions for the synthesis of substituted imidazo[4,5-c]pyridines
Wilson, Robert J.,Rosenberg, Adam J.,Kaminsky, Lauren,Clark, Daniel A.
, p. 2203 - 2212 (2014/04/03)
Imidazo[4,5-c]pyridines were synthesized in three steps utilizing a palladium-catalyzed amidation/cyclization strategy. N-Aryl substrates were synthesized using copper-catalyzed amidation of 3-amino-N-Boc-4-chloropyridine. Complementary protocols for the selective chlorination of imidazo[4,5-c] pyridines at the C2 and C7 positions were also developed.
NEW CYCLIZATION REACTIONS OF 3-DIALKYLAMINO-4-AMINOPYRIDINES UNDER CONDITIONS OF NITRATION
Miura, Yutaka,Takaku, Sakae,Nawata, Yoshikaru,Hamana, Masatomo
, p. 1491 - 1495 (2007/10/02)
Treatment of 3-dialkylamino-4-aminopyridines (1) with nitric and sulfuric acids affords imidazopyridine derivatives (2,3 and 4) and 1,2,3-triazolopyridine 2-oxides (5) by cyclization reaction of the corresponding 4-nitroaminopyridines.
