76480-99-4Relevant articles and documents
Synthesis of 3-hydroxy-5-per(poly)fluoroalkyl pyrazoles
Hu, Qiao-Sheng,Guan, Hui-Ping,Hu, Chang-Ming
, p. 51 - 54 (1995)
Treatment of ethyl α-per(poly)fluoroalkyl acetates 1 or ethyl α-iodo-β-per(poly)fluoroalkyl acrylates 2 with hydrazine gives 3-hydroxy-5-per(poly)fluoroalkyl pyrazoles 3 in excellent yield.The effect of halogens on the per(poly)fluoroalkyl chain and the reaction conditions were studied. - Keywords: Synthesis; Hydroxyper(poly)fluoroalkyl pyroles; NMR spectroscopy; IR spectroscopy; Mass spectrometry
A systematic exploration of nickel-pyrazolinato chemistry with alkali metals: New cages from serendipitous assembly
Aromi, Guillem,Bell, Aidan R.,Helliwell, Madeleine,Raftery, James,Teat, Simon J.,Timco, Grigore A.,Roubeau, Olivier,Winpenny, Richard E. P.
, p. 3024 - 3032 (2007/10/03)
The preparation and properties of fourteen novel paramagnetic [NiIIx] aggregates bridged by pivalate, pyrazolinolate and in most cases hydroxide are reported. A rich structural diversity has been achieved by changing the nature of the alkali of the base used during the synthesis, leading to the nuclearities [NiII4NaI4] (2, 3, 4), [NiII5-NAI4] (5, 6, 7), [NiII5LiI6] (8), [NiII8MI2] (M = K (9, 10), Rb (11, 12), Cs (13, 14) and [NiII8] (15). All compounds have been characterised by single-crystal X-ray diffraction; however, full crystallographic details are given only for the representative molecules [Ni4Na4- (fpo)4(piv)8(Hpiv)8] (2), [Ni5Na4(OH)2- (mpo)4(piv)8(Hpiv)2(MeCN)2] (5), [Ni5Li6(OH)2 (fpo)2(piv)12(Hpiv)4] (8) [Ni8K2(OH)4(ppo) 4(piv)10(Hppo)2- (Hpiv)2(MeCN)2] (9), [Ni8Rb2(OH)4- (ppo)4(piv)10(Hppo) 2(Hpiv)2(MeCN)2] (11), [Ni8Cs2(OH)4(ppo) 4(piv)10(Hppo)2- (Hpiv)2(MeCN)2] (13) and [Ni8(OH)4-(mpo)2(PhCH 2CO2)10(Hmpo)8] (15). Variable-temperature bulk magnetisation measurements have been performed for each type of complex. The [NiII4NaI4] clusters show intramolecular antiferromagnetic coupling and a spin ground state of S = 0. Complexes of the type [NiII5NaI4] also display antiferromagnetic superexchange, leading to an S=1 spin ground state. The molecule with nuclearity [NiII5LiI6], in contrast, exhibits ferromagnetic interactions, resulting in the presence of low energy states with high multiplicity, and a spin ground state S>1. The [NiII5MI2] and [NiII8] clusters have the same topology of spin carriers, which display predominantly antiferromagnetic interactions to yield a diamagnetic ground state. The coupling within these octanuclear NiII clusters is rationalised in terms of the nature of the Ni-O-Ni angles within the core.
Synthesis of Fluorinated Analogues of Geraniol
Poulter, C. Dale,Wiggins, Paul L.,Plummer, Thomas L.
, p. 1532 - 1538 (2007/10/02)
Syntheses of 3-(fluoromethyl)geraniol (4), 3-(difluoromethyl)geraniol (14), and 3-(trifluoromethyl)geraniol (20) are described.The key reaction in the routes to alcohols 4 and 20 which establishes the geranyl Z stereochemistry at the C(2)-C(3) double bond is the cis addition of (4-methylpent-3-en-1-yl)copper reagents to derivatives of ethyl 2-butynoate bearing appropriate functional groups at C(4).Attempts to prepare difluoromethyl alcohol 14 by similar routes were unsuccessful.However, the carbon skeleton of 14 was constructed by a Wittig condensation of 1,1-difluoro-6-methylhept-5-en-2-one (12) with triethyl phosphonoacetate in a reaction that yielded a 72:28 ratio of geranyl/neryl isomers.