76497-45-5

Upstream product

• 54445-64-6 (1R,2S)-(2-hydroxymethylcyclobutyl)methanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 4462-96-8 3-oxabicyclo[3.2.0]heptane-2,4-dione 
• 869-10-3 diethyl 2,5-dibromoadipate 
• 2607-03-6 dimethyl cis-1,2-cyclobutanedicarboxylate 
• 412346-70-4 1-cyano-cyclobutane-1,2-dicarboxylic acid diethyl ester 
• 7371-67-7 dimethyl trans-1,2-cyclobutane dicarboxylate 
• 7371-64-4 trans-(cyclobutane-1,2-diyl)dimethanol 
• 77774-01-7 (1R,4S)-(4-hydroxymethylcyclobut-2-enyl)methanol 

Downstream Products

• 22836-01-7 3-Benzyliden-cis-bicyclo<3,2,0>heptan 

Relevant academic research and scientific papers

Understanding the Structure–Polymerization Thermodynamics Relationships of Fused-Ring Cyclooctenes for Developing Chemically Recyclable Polymers

Polymers that can be chemically recycled to their constituent monomers offer a promising solution to address the challenges in plastics sustainability through a circular use of materials. The design and development of monomers for next-generation chemical

A Stereochemical Study of the Thermolysis of cis-anti- and trans-1,2-Dimethyl-cis-3,4-dideuteriocyclobutane

The stereochemistry of the fragmentation and isomerization of cis-anti- and trans-1,2-dimethyl-cis-3,4-dideuteriocyclobutane at 510 deg C is reported.The cis-anti-cis isomer undergoes fragmentation to yield cis/trans-propene-d1 (1.5/1, major pathway), cis/trans-2-butene (1.4/1), and cis/trans-ethylene-d2 (1/1, minor pathway).Recovered cis-1,2-dimethylcyclobutane-d2 containing approximately 40percent of the double rotation product relative to the product of single methyl rotation, trans-1,2-dimethylcyclobutane-d2.The trans isomer behaves similarly, yielding cis/trans-propene-d1 (1/1, major pathway), cis/trans-2-butene (1/5), and cis/trans-ethylene-d2 (1/1, minor pathway).Recovered cis-1,2-dimethylcyclobutane-d2 from thermolysis of the trans isomer consists mainly of equal amounts of cis-anti-cis- and cis-syn-cis-1m2-dimethylcyclobutane-d2 as analyzed by NMR.On the basis of product composition, the thermal chemistry of this system can be explained as proceeding through 2,5-hexanediyl (major pathway) and 3-methyl-1,4-pentanediyl (minor pathway).On the basis of the observed stereochemistry, it can be concluded that the lifetimes of both 2,5-hexanediyl and 3-methyl-1,4-pentanediyl are similar and of the same order as bond rotations at a radical center.This suggests that the gauche to trans conformational changes involving carbon-carbon bond rotation at carbon 2 and 3 of 1,4-diyls may not be competitive with fragmentation.

Models for the Ion-Pair Cluster Mechanism in Nucleophilic Substitution Reactions

Several bis(alkoxytriphenylphosphonium) salts have been prepared.When sterically constrained, as close neighbors, the leaving groups of these cations react rapidly at room temperature with negative nucleophiles to produce the expected substitution product.When sterically unconstrained, these types of functional groups behave as if they were mono(alkoxytriphenylphosphonium) salts, substituting very slowly or not at all at room temperature.The ion-pair cluster mechanism is discussed in light of these results.