76513-94-5

Basic information

• Product Name: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(trifluoromethyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
• Synonyms: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(trifluoromethyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
• CAS NO: 76513-94-5
• Molecular Weight: 446.34
• Mol File: 76513-94-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(trifluoromethyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(trifluoromethyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(76513-94-5)
• EPA Substance Registry System: (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-(trifluoromethyl)-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate(76513-94-5)

Safety Data

• Hazardous Substances Data: 76513-94-5(Hazardous Substances Data)

Upstream product

• 680-15-9 2,2-difluoro-2-(fluorosulfonyl)acetate 
• 74465-47-7 (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(6-bromo-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate 

Downstream Products

• 368421-66-3 5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-9-(β-D-ribofuranosyl)-6-(trifluoromethyl)-purine 
• 368421-65-2 5'-O-(4,4'-dimethoxytrityl)-9-(β-D-ribofuranosyl)-6-(trifluoromethyl)-purine 

Relevant articles and documents

Synthesis and analysis of RNA containing 6-trifluoromethylpurine ribonucleoside.

We report the synthesis of a 5'-DMT-2'-TBDMS-protected phosphoramidite of 6-trifluoromethylpurine ribonucleoside ((TFM)P) and its use in the site-specific incorporation of 6-trifluoromethylpurine into RNA. Properties of (TFM)P-substituted RNA suggest it will be valuable in the study of RNA structure and the binding of RNA-modifying enzymes, particularly the RNA-editing adenosine deaminases. Reaction: see text.