76526-59-5Relevant academic research and scientific papers
REACTION OF O-TRIMETHYLSILYLATED CYANOHYDRINS WITH α-BROMOESTERS: A NEW SYNTHESIS OF TETRONIC ACIDS
Krepski, Larry R.,Lynch, Laurie E.,Heilmann, Steven M.,Rasmussem, Jerald K.
, p. 981 - 984 (2007/10/02)
Tetronic acids and β-keto-γ-butyrolactones are easily prepared by the zinc induced reaction of O-trimethylsilylated cyanohydrins and α-bromoesters.
Metabolites of the Higher Fungi. Part 19. Serpenone, 3-Methoxy-4-methyl-5-prop-1-enylfuran-2(5H)-one, a new γ-Butyrolactone from the Fungus Hypoxylon serpens (Barrons strain) (Persoon ex Fries)Kickx
Anderson, John R.,Edwards, Raymond L.,Whalley, Anthony J. S.
, p. 215 - 222 (2007/10/02)
Culture solutions of the fungus Hypoxylon serpens (Barrons strain) contain a new butyrolactone as the major metabolite, which has been identified as 3-methoxy-4-methyl-5-prop-1-enylfuran-2(5H)-one (2),and small quantities of the reduced analogue, 3-methoxy-4-methyl-5-propylfuran-2(5H)-one (3); the structures have been established by synthesis of compound (3).A new rapid synthesis of the isomeric 4-methoxy-3,5-disubstituted analogues is described and the two groups of compounds are compared spectroscopically.
Synthesis of 4-Substituted 2-Methyltetronic Acid Derivatives
Yamada, Takateru,Hagiwara, Hisahiro,Uda, Hisashi
, p. 838 - 839 (2007/10/02)
Condensation of the carbanion derived from methyl (E)-3-methoxy-2-methylprop-2-enoate with aldehydes provides a one step synthesis of 4-substituted methyl 2-methyltetronates, which are transformed into the free acids and 4-alkylidene derivatives.
