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76541-91-8

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76541-91-8 Usage

General Description

7-Amino-4-hydroxy-1,8-naphthyridin-2(1H)-one is a chemical compound with the molecular formula C9H7N3O2. It belongs to the class of naphthyridin-2(1H)-one derivatives and is commonly used as an intermediate in the synthesis of pharmaceuticals and research chemicals. 7-AMino-4-hydroxy-1,8-naphthyridin-2(1H)-one is known for its pharmacological properties and is used in the development of drugs targeting various diseases and conditions. Its unique molecular structure and properties make it a valuable component in the field of medicinal chemistry, and it is an important compound in the study and development of new therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 76541-91-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,5,4 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 76541-91:
(7*7)+(6*6)+(5*5)+(4*4)+(3*1)+(2*9)+(1*1)=148
148 % 10 = 8
So 76541-91-8 is a valid CAS Registry Number.

76541-91-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 7-amino-4-hydroxy-1H-1,8-naphthyridin-2-one

1.2 Other means of identification

Product number -
Other names 7-Amino-1,8-naphthyridine-2,4-diol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76541-91-8 SDS

76541-91-8Relevant articles and documents

COMPOUNDS AND METHODS FOR INHIBITING mTOR

-

Page/Page column 77-78, (2017/03/14)

Compounds having activity as mTOR inhibitors are disclosed. The compounds have the following structure (I) including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R3, R4, and A are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Synthesis of 1,8-naphthyridine derivatives: Potential antihypertensive agents - Part VII

Ferrarini, Pier Luigi,Mori, Claudio,Badawneh, Muwaffag,Calderone, Vincenzo,Calzolari, Lorella,Loffredo, Tiziana,Martinotti, Enrica,Saccomanni, Giuseppe

, p. 383 - 397 (2007/10/03)

A series of 2-(carbethoxypiperazinyl)- and 2-piperazinyl-1,8- naphthyridine derivatives, variously substituted, have been synthesized and pharmacologically investigated for their antihypertensive activity. Some of them exhibited a significant and prolonged decrease of the mean arterial pressure (MAP) on spontaneously hypertensive rats. For this series of compounds, on the basis of the pharmacological results obtained, no structure-activity relationship can be deduced at this time. Moreover, the most active and representative compounds 11b, 12a and 16b were investigated by means of in vitro pharmacological functional studies and in vivo, as diuretic agents, to determine a possible mechanism of the antihypertensive activity, which is unknown for the moment.

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